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Cincinnati Reds vs Chicago Cubs Prediction 8/28/2026 Today’s MLB Picks

Aug 22, 2026; Seattle, Washington, USA; Chicago Cubs pitcher David Peterson (19) throws against the Seattle Mariners during the sixth inning at T-Mobile Park. Mandatory Credit: Joe Nicholson-Imagn Images

Aug 22, 2026; Seattle, Washington, USA; Chicago Cubs pitcher David Peterson (19) throws against the Seattle Mariners during the sixth inning at T-Mobile Park. Mandatory Credit: Joe Nicholson-Imagn Images

MATCHUP Cincinnati Reds Chicago Cubs
Team Records 63-71 76-58
Spread +1.5 -131 -1.5 109
Moneyline +170 -183
Total Over 8.5 (-101) Under 8.5 (-119)
Where Wrigley Field, Chicago, Illinois
When Friday, August 28, 2026
Time 02:20 PM EDT
TV ESPN Unlmtd
In this article, we will formulate a Reds vs Cubs Prediction for this MLB matchup on Friday, August 28th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview


The Chicago Cubs have a 76-58 record this season and sit in second place in the NL Central. They have a 38-27 home record and are coming off a 0-2 road loss against the Diamondbacks. They will face the Brewers and the Marlins next.

The Chicago Cubs have a .249 batting average this season, .338 OBP, and .422 slugging percentage. Chicago’s pitching staff has a 4.09 ERA and 1.25 WHIP. Pete Crow-Armstrong is the Cubs’ best hitter with a .276 batting average, while leading the team in RBI with 83, also adding a team-high 33 home runs.

David Peterson (L) is the projected starting pitcher for the Cubs, has a 7-7 record, 5.17 ERA, and 1.50 WHIP.

Cincinnati Reds Preview


The Cincinnati Reds have a 63-71 record this season and sit in fifth place in the NL Central. They have a 31-35 road record and are coming off a 10-9 road win against the Giants. They will face the Padres and the Brewers next.

The Cincinnati Reds have a .227 batting average this season, .306 OBP, and .392 slugging percentage. Cincinnati’s pitching staff has a 4.55 ERA and 1.41 WHIP. Elly De La Cruz is the Reds’ best hitter with a .265 batting average. Sal Stewart leads the team in RBI with 100, also adding a team-high 28 home runs.

Rhett Lowder (R) is the projected starting pitcher for the Reds, has a 5-8 record, 5.13 ERA, and 1.47 WHIP.

Cincinnati Reds @ the Chicago Cubs Betting Trends: August 28, 2026


Why the Chicago Cubs will win

Why the Cincinnati Reds will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Cincinnati Reds Player Prop Facts

Matchup/League Facts

Reds vs Cubs Prediction


The Cubs are 6-1 in their last 7 meetings against the Reds and have won their last four meetings in Chicago.

In this Reds vs Cubs Prediction, the Cubs are coming as -180 home favorites. I don’t like the pitching in this matchup, as both starters have been struggling this season with a combined 10.30 ERA. Lowder has been even weaker on the road for the Reds with a 6.92 road ERA, while Peterson is also weaker at home with a 6.16 ERA. Both offenses have been red-hot lately, scoring 11.8 runs per game combined in their last 5 games and 12.1 against the opposing starter throwing hand. Take the over 8 in this one.

Nikos Lagouretos's Pick: Over 8

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