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Chicago White Sox vs New York Mets Prediction 5/28/25 MLB Picks

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New York Mets (34-21) vs Chicago White Sox (17-38)

Game Info: Wednesday, May 28, 2025 at 1:10 pm (Citi Field)

The Line: Betting Odds: New York Mets -250 / Chicago White Sox +205 — Over/Under: 8

(Get latest betting odds)

The Chicago White Sox and New York Mets meet Wednesday in MLB action at Citi Field. Here’s a Chicago White Sox vs New York Mets Prediction. This article will include a Chicago White Sox vs New York Mets Pick.

Chicago White Sox Betting Preview

The Chicago White Sox are 17-38 on the year and play the Orioles, Tigers, and Royals next. The Chicago White Sox are batting .220 on the season, have a .292 OBP, and a .341 slugging percentage. The Chicago White Sox pitching staff has a 4.11 ERA and a 1.38 WHIP. Lenyn Sosa leads the Chicago White Sox with 49 hits and 16 RBI, while Miguel Vargas and Andrew Vaughn have combined for 82 hits and 45 RBI. 

Shane Smith gets the ball for the Chicago White Sox, and he is 1-3 with a 2.36 ERA and 49 strikeouts this season. This will be Smith’s first career game against the New York Mets.

New York Mets Betting Preview

The New York Mets are 34-21 on the year and play the Rockies, Dodgers, and Rockies next. The New York Mets are batting .247 on the season, have a .329 OBP, and a .406 slugging percentage. The New York Mets pitching staff has a 2.80 ERA and a 1.25 WHIP. Francisco Lindor leads the New York Mets with 60 hits and 31 RBI, while Pete Alonso and Juan Soto have combined for 104 hits and 67 RBI.

Griffin Canning gets the ball for the New York Mets, and he is 5-1 with a 2.88 ERA and 47 strikeouts this season. Canning is 3-0 with a 1.89 ERA and 23 strikeouts in his career against the Chicago White Sox.

Why the New York Mets will win

Why the Chicago White Sox will win

New York Mets Player Prop Facts

Chicago White Sox Player Prop Facts

Chicago White Sox vs New York Mets Prediction

Another White Sox game, another chance to fade them and make a profit. I want nothing to do with the White Sox, the worst team in baseball over the last three years. This season alone, the White Sox have lost the third-most money for MLB bettors. Only the Orioles and Rockies have lost bettors more money. The Mets are having a great week, and Canning has been sharp this season with his 2.88 ERA and 1.32 WHIP. In 23.2 home innings, Canning has a 2.66 ERA and a .195 allowed batting average. Give me the Mets and the RL for max betting value.

Randy Chambers's Pick: New York Mets -1.5

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