| MATCHUP | Chicago Cubs | San Diego Padres |
|---|---|---|
| Team Records | 18-12 | 19-10 |
| Spread | -1.5 141 | +1.5 -171 |
| Moneyline | -115 | -105 |
| Total | Over 9 (-115) | Under 9 (-105) |
| Where | Petco Park, San Diego, California | |
| When | Wednesday, April 29, 2026 | |
| Time | 04:10 PM EDT | |
| TV | MLB.TV | |
Chicago Cubs Betting Preview
The Chicago Cubs are 18-12 on the year and play the Diamondbacks and Reds next. The Chicago Cubs are batting .261 on the season and have a .353 OBP, and a .424 slugging percentage. The Chicago Cubs pitching staff has a 4.01 ERA and a 1.20 WHIP. Nico Hoerner leads the Chicago Cubs with 36 hits and 26 RBI, while Alex Bregman and Pete Crow-Armstrong have combined for 58 hits and 21 RBI.
Jameson Taillon gets the ball for the Chicago Cubs, and he is 1-1 with a 4.55 ERA and 25 strikeouts this season. Taillon is 2-0 with a 2.40 ERA and 23 strikeouts in his career against the San Diego Padres.
San Diego Padres Betting Preview
The San Diego Padres are 19-10 on the year and play the Giants and White Sox next. The San Diego Padres are batting. 238 on the season, have a .312 OBP, and have a .386 slugging percentage. The San Diego Padres pitching staff has a 4.20 ERA and a 1.30 WHIP. Xander Bogaerts leads the San Diego Padres with 30 hits and 17 RBI, while Ramon Laureano and Fernando Tatis Jr. have combined for 54 hits and 30 RBI.
Matt Waldron gets the ball for the San Diego Padres, and he is 0-1 with a 12.46 ERA and 7 strikeouts this season. This will be Waldron’s first career game against the Chicago Cubs.
Why the San Diego Padres will win
- The Padres have won each of their last eight day games against NL Central opponents following a loss.
- The Cubs have lost each of their last seven games at Petco Park following a win.
- The Cubs have failed to cover the run line in each of their last eight day games against teams that held a winning record.
- The Padres have covered the run line in each of their last eight day games against NL Central opponents following a loss.
- The Cubs have trailed after 3 innings in three of their last four day games against opponents that held a winning record.
- The Padres have led after 5 innings in four of their last five home games against opponents that held a winning record.
Why the Chicago Cubs will win
- The Cubs have won each of their last eight games as favorites against National League opponents.
- The Cubs have covered the run line in each of their last four games as favorites.
- The Padres have failed to cover the run line in three of their last four games as underdogs after playing the previous day.
- The Cubs have led after 3 innings in seven of their last eight Wednesday games against opponents that held a winning record.
Total Runs Facts
- Seven of the Cubs’ last eight road games have gone OVER the total runs line.
- Each of the Padres’ last four games against NL Central opponents has gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the last nine games between the Cubs and Padres at Petco Park.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of Jameson Taillon’s last eight road appearances as a starter.
San Diego Padres Player Prop Facts
- Xander Bogaerts has recorded at least one hit in each of the Padres’ last nine games against NL Central opponents that held a winning record.
- Luis Campusano has hit a home run in three of his last four appearances with the Padres against NL opponents.
Chicago Cubs Player Prop Facts
- Seiya Suzuki has hit a home run in five of the Cubs’ last eight games against NL opponents.
- Jameson Taillon has recorded a win in three of his last four appearances with the Cubs as road favorites against NL opponents.
- Jameson Taillon has recorded five or more strikeouts in five of his last six appearances with the Cubs as favorites against NL West opponents.
- Alex Bregman has recorded at least one hit in each of his last six appearances with his team as a favorite against the Padres.
- Nico Hoerner ranks T10th in the league in Steals (7) this season.
Matchup/League Facts
- The Padres rank T8th in the league for triples this season (4).
- The Padres rank 23rd in the league for on-base percentage this season (.312).
- The Cubs rank 3rd in the league for runs scored this season (164).
- The Cubs rank 3rd in the league for hits this season (270).
Chicago Cubs vs San Diego Padres Prediction
I’ve been blindly backing the Padres this season and it’s worked up to this point. The problem here is Waldron has yet to pitch consistently in his career and he’s been terrible through 8.2 innings this season with a 12.46 ERA and 2.31 WHIP. The Cubs have played well in their own right and while Taillon has had his struggles as well, it’s nothing compared to what Waldron is dealing with. Pick a spot; I like the Cubs on Wednesday.