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Cardinals vs Cubs Prediction 8/16/2026 Today’s MLB Picks

Jul 8, 2026; St. Louis, Missouri, USA; St. Louis Cardinals right fielder Jordan Walker (18) reacts after hitting a one run double against the Milwaukee Brewers during the first inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

Jul 8, 2026; St. Louis, Missouri, USA; St. Louis Cardinals right fielder Jordan Walker (18) reacts after hitting a one run double against the Milwaukee Brewers during the first inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

MATCHUP St. Louis Cardinals Chicago Cubs
Team Records 62-61 72-52
Spread +1.5 -156 -1.5 129
Moneyline +134 -162
Total Over 9 (100) Under 9 (-120)
Where Wrigley Field, Chicago, Illinois
When Sunday, August 16, 2026
Time 03:00 PM EDT
TV ABC
In this article we will formulate a Cardinals vs Cubs prediction for this MLB game on Sunday, August 16th at Wrigley Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 62-61 this year after they split the first two games by scores of 0-3 and 8-4. In game two, St. Louis blew an early 3-0 lead, but they scored the next five runs to pull away in the win. The Cardinals recorded seven hits and they committed one error in the game, while they were led by Baez, who went 3-4 with three home runs and five RBIs. McGreevy allowed five hits and zero earned runs over 6.0 innings for the win, while Stanek allowed one earned run in relief. Prior to this series, St. Louis won two out of three against the Phillies and two out of three against the Rockies. 

This season, St. Louis has a 4.04 ERA with a 1.34 WHIP and a .252 opponent batting average, while they have scored 537 runs with a .239 batting average and a .315 on base percentage. Jordan Walker has led the Cardinals with 23 home runs and 84 RBIs, while Alec Burleson has added 20 home runs and 86 RBIs. The projected starting pitcher for St. Louis is Hunter Dobbins, who is 2-3 with a 3.40 ERA and a 1.31 WHIP over 45.0 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 72-52 this season after they lost game two by a score of 4-8 on Saturday. Chicago scored three runs in the second inning, but didn’t score again until the eighth in the loss. The Cubs recorded eight hits in the game and they were led by Conforto, who went 1-2 with one home run and three RBIs. Boyd allowed five hits and seven earned runs over 5.1 innings for the loss, while Rea allowed one earned run in relief. Prior to this series, Chicago won two out of three against the Nationals and two out of three against the Royals. 

This season, Chicago has a 4.10 ERA with a 1.25 WHIP and a .244 opponent batting average, while they have scored 641 runs with a .249 batting average and a .338 on base percentage. Pete Crow-Armstrong has led the Cubs with 27 home runs and 73 RBIs, while Dansby Swanson has added 18 home runs and 66 RBIs. The projected starting pitcher for Chicago is Edward Cabrera, who is 5-4 with a 5.10 ERA and a 1.40 WHIP over 72.1 innings pitched this season. 

Why the Chicago Cubs will win

Why the St. Louis Cardinals will win

Total Runs Facts

Chicago Cubs Player Prop Facts

St. Louis Cardinals Player Prop Facts

Cardinals vs Cubs Prediction

St. Louis bounced back from their game one loss with a win on Saturday and they are back above .500 for the season. The Cardinals are 30-27 on the road this year, while the Cubs are 36-25 at home. Chicago has lost two of their last three games and they have allowed 6+ runs in four of their last five. The Cubs are starting Cabrera, who has been on the IL since June, while Dobbins has allowed two earned runs or fewer in three of his last four starts. Take the Cardinals to win again here.

David Racey's Pick: Cardinals ML

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