Boston Red Sox vs Toronto Blue Jays Prediction 4/30/25 MLB Picks

The Boston Red Sox and the Toronto Blue Jays meet Wednesday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

Lucas Giolito will make his Red Sox debut here after not pitching in the 2024 season. In his last 5 starts against the Blue Jays, Giolito is 0-3 with a 6.33 ERA and 26 strikeouts. The Toronto Blue Jays did not have a starting pitcher announced at the time that this article was posted.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to build on their 10-2 win over the Blue Jays from Tuesday’s matchup to improve to 18-14 on the year. After this series, the Red Sox will head home for a series against the Minnesota Twins.

Red Sox Win Three In A Row

Alex Bregman leads the Red Sox with 40 hits, including a team-high 11 doubles, along with 6 home runs and 23 RBIs, while Rafael Devers has added 25 hits with 8 doubles, 5 home runs and 18 RBIs this season. Trevor Story added 32 hits with 5 home runs, 16 RBIs, and 6 stolen bases, while Jarren Duran has 36 hits with 8 doubles, 3 triples, 2 home runs, 16 RBIs, and a team-high 9 stolen bases. Kristian Campbell added 31 hits with 8 doubles, 4 homers, and 12 RBIs, while Wilyer Abreu has 6 home runs with 21 RBIs and 4 stolen bases, and Ceddanne Rafaela has 2 homers, 15 RBIs, and 6 stolen bases this season.

Why the Boston Red Sox will win

• The Blue Jays have lost eight of their last nine games.
• The Red Sox have won seven of their last eight games at Rogers Centre against AL East opponents that held a losing record.
• The Blue Jays have failed to cover the run line in eight of their last nine games.
• The road team has covered the run line in eight of the last nine games between the Red Sox and Blue Jays.

Boston Red Sox Player Prop Facts

• Alex Bregman has hit at least one home run in three of his last four road appearances against AL East opponents.
• Lucas Giolito has recorded a win in each of his last five appearances against AL East opponents that held a losing record.
• Rafael Devers has recorded an RBI in each of the Red Sox’s last four games against AL opponents.
• Lucas Giolito has recorded five or more strikeouts in each of his four previous appearances at Rogers Centre.
• Alex Bregman has scored at least one run in seven of his last eight appearances after playing the previous day.
• Alex Bregman has recorded at least one Single in each of the Red Sox’s last six games.
• Alex Bregman has recorded at least one hit in each of the Red Sox’s last nine games against AL opponents.
• Alex Bregman ranks 3rd in the league in Hits (40) this season.

Toronto Blue Jays Recap

The Toronto Blue Jays will be out to rebound from their loss at the hands of the BoSox in Tuesday’s matchup to fall to 13-16 on the year. After this series, the Blue Jays will take on the Cleveland Guardians at home.

Blue Jays Drop Three Straight & 8 Of Last 9

George Springer has 26 hits and Bo Bichette has 36 hits, with Springer adding 2 home runs, a triple, 7 doubles, and 12 RBIs while Bichette has 9 doubles and 13 RBIs. Andres Gimenez has added 18 hits with 4 doubles and a team-high 3 home runs and 8 RBIs this season, along with 8 stolen bases, while Anthony Santander has a team-high 30 strikeouts so far this season. Vladimir Guerrero Jr. also has 3 homers, 6 doubles, and 14 RBIs, while Springer also has a .313 batting average up to this point in the year.

Why the Toronto Blue Jays will win

• The Blue Jays have won 11 of their last 12 night games at Rogers Centre following a home loss.
• The Red Sox have lost nine of their last 12 night games after playing the previous day.
• The Blue Jays have covered the run line in five of their last six games against the Red Sox.

Toronto Blue Jays Player Prop Facts

• Vladimir Guerrero Jr. has hit a home run in two of the Blue Jays’ last three night games against opponents that held a winning record.
• George Springer has recorded a Double in three of the Blue Jays’ last four home games against opponents that held a winning record.
• Vladimir Guerrero Jr. has recorded at least one RBI in six of the Blue Jays’ last seven games against AL East opponents.
• Bo Bichette has scored at least one run in each of his last six home appearances against AL East opponents that held a winning record.
• Bo Bichette has recorded at least one Single in each of the Blue Jays’ last seven home games against AL opponents.
• Alejandro Kirk has recorded at least one hit in each of his last seven home appearances against the Red Sox after playing the previous day.
• Andres Gimenez ranks T8th in the league in Steals (8) this season.

Total Runs Facts

• Nine of the Blue Jays’ last 10 night games against American League opponents have gone UNDER the total runs line.
• Eight of the Red Sox’s last nine night games against American League opponents have gone OVER the total runs line.

Boston Red Sox vs. Toronto Blue Jays Prediction

I’m leaning towards the Blue Jays here. I’d like to know who Toronto is starting here, but it’s hard for me to get behind Lucas Giolito at the best of times, but coming into the season, late, making his debut against a Blue Jays team that’s had his number for the better part of his career and who’s to say that Giolito could be on a pitch count here, which would definitely tax a subpar Red Sox bullpen as well. I’ll roll with the Jays at home in this one.

Chris Ruffolo's Pick: Toronto Blue Jays +100