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Boston Red Sox vs Houston Astros Prediction 4/1/2026 Today’s MLB Picks

Mar 30, 2026; Houston, Texas, USA; Boston Red Sox right fielder Wilyer Abreu (52) drives in a run with a double during the seventh inning against the Houston Astros at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

Mar 30, 2026; Houston, Texas, USA; Boston Red Sox right fielder Wilyer Abreu (52) drives in a run with a double during the seventh inning against the Houston Astros at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

MATCHUP Boston Red Sox Houston Astros
Team Records 1-5 5-2
Where Daikin Park, Houston, Texas
When Wednesday, April 1, 2026
Time 02:10 PM EDT
TV MLB.TV

The Boston Red Sox and the Houston Astros meet Wednesday in MLB action from Daikin Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston Red Sox vs. Houston Astros prediction.

Starting Pitching Matchup

The Boston Red Sox will send out Garrett Crochet for the start here and Crochet is 1-0 with a 0.00 ERA and 8 strikeouts this season. Mike Burrows will get the nod for the Astros here and Burrows is 0-1 with a 7.94 ERA and 6 strikeouts this season. 

Boston Red Sox Recap

The Boston Red Sox come into this game looking to bounce back from their 9-2 loss at the hands of the Astros on Tuesday to sit at 1-4 this season. After this series, the Red Sox will head home for a series against San Diego.

Red Sox Lose 4th In A Row

Wilyer Abreu leads the Red Sox with 8 hits including 3 doubles, 2 home runs and 5 RBIs while Trevor Story has a homer and 2 RBIs and Marcelo Mayer’s added 3 hits with a pair of doubles as well. Roman Anthony has 4 hits so far this season while Carlos Narvaez has added 4 hits and Connor Wong has a pair of doubles. 

Houston Astros Recap

The Houston Astros come into this game looking to add on to their win over Boston from Tuesday’s game to improve to 4-2 this season. After this series, the Astros will head on the road for a series against the Athletics.

Astros Pick Up Fourth Straight Win

Yordan Alvarez has 8 hits with a pair of doubles, 3 home runs and 6 RBIs while Christian Walker has 7 hits with 5 doubles and 6 RBIs of his own. Isaac Paredes has 4 hits with 3 doubles and 4 RBIs while Carlos Correa has 7 hits with a double and 4 RBIs. Jose Altuve and Yainer Diaz each have 3 RBIs as well this season. 

Boston Red Sox @ Houston Astros Betting Trends: April 1, 2026

Why the Houston Astros will win

Why the Boston Red Sox will win

Total Runs Facts

Houston Astros Player Prop Facts

Boston Red Sox Player Prop Facts

Matchup/League Facts

Boston Red Sox vs. Houston Astros Prediction

I’m on the Red Sox here. I just think the Red Sox have a clear pitching edge with Crochet getting the start here and while the Red Sox have been struggling, it feels like Crochet is the stopper as he was dominant in debut and was responsible for the lone win the Red Sox have so far this season. Houston’s up against it here with Mike Burrows pitching, and I think the Red Sox pick up the win when all is said and done. Give me Boston.

Chris Ruffolo's Pick: Boston -155

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