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Boston Red Sox vs Baltimore Orioles Prediction 4/2/25 MLB Picks

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Baltimore Orioles (3-2) vs Boston Red Sox (1-4)

Game Info: Wednesday, April 2, 2025 at 6:35 pm (Oriole Park at Camden Yards)

The Line: Betting Odds: Baltimore Orioles +100 / Boston Red Sox -120 — Over/Under: 7.5

(Get latest betting odds)

The Boston Red Sox and Baltimore Orioles meet on Wednesday in MLB action at Oriole Park at Camden Yards. Here’s a Boston Red Sox vs Baltimore Orioles Prediction. This article will include a Boston Red Sox vs Baltimore Orioles Pick.

Boston Red Sox Betting Preview

The Boston Red Sox are 1-4 on the year and play the Cardinals, Blue Jays, and White Sox next. The Boston Red Sox are batting .201 on the season, have a .289 OBP, and a .302 slugging percentage. The Boston Red Sox pitching staff has a 4.61 ERA and a 1.29 WHIP. Wilyer Abreu leads the Boston Red Sox with 7 hits and 6 RBI, while Jarren Duran and Krisitan Campbell have combined for 12 hits and 5 RBI. 

Garrett Crochet gets the ball for the Boston Red Sox, and he is 0-0 with a 3.60 ERA and 4 strikeouts this season. Crochet is 0-1 with a 2.25 ERA and 13 strikeouts in his career against the Baltimore Orioles.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 3-2 on the year and play the Royals, Diamondbacks, and Blue Jays next. The Baltimore Orioles are batting .305 on the season, have a .364 OBP, and a .517 slugging percentage. The Baltimore Orioles pitching staff has a 4.60 ERA and a 1.40 WHIP. Tyler O’Neill leads the Baltimore Orioles with 8 hits and 5 RBI, while Jordan Westburg and Cedric Mullins have combined for 14 hits and 13 RBI.

Zach Eflin gets the ball for the Baltimore Orioles, and he is 1-0 with a 3.00 ERA and 2 strikeouts this season. Eflin is 3-0 with a 5.10 ERA and 35 strikeouts in his career against the Boston Red Sox.

Why the Baltimore Orioles will win

Why the Boston Red Sox will win

Boston Red Sox vs Baltimore Orioles Prediction

This should be a fun matchup between two above-average pitchers in Crochet and Eflin, and you can make a case for either side. I’m siding with the Orioles and the even money, as the O’s have been better offensively through five games, and that includes scoring eight or more runs in three of those contests. The Red Sox will get their act together at some point, but these last four games have been a tough watch. Rafael Devers is key to the Red Sox’s success, and he has yet to get a hit this season and has 15 strikeouts. Triston Casas hasn’t been much better, with just one hit and seven strikeouts. The value is with the Orioles and the better price.

Randy Chambers's Pick: Baltimore Orioles +100

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