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Baltimore Orioles vs New York Yankees Prediction 9/25/2026 Today’s MLB Picks

Sep 23, 2026; Baltimore, Maryland, USA;  Baltimore Orioles catcher Yohel Pozo (79) falls while swinging at a pitch during the eighth inning in Game 2 of a doubleheader against the Toronto Blue Jays at Oriole Park at Camden Yards.  Mandatory Credit: Daniel Kucin Jr.-Imagn Images

Sep 23, 2026; Baltimore, Maryland, USA; Baltimore Orioles catcher Yohel Pozo (79) falls while swinging at a pitch during the eighth inning in Game 2 of a doubleheader against the Toronto Blue Jays at Oriole Park at Camden Yards. Mandatory Credit: Daniel Kucin Jr.-Imagn Images

MATCHUP Baltimore Orioles New York Yankees
Team Records 78-81 92-67
Spread +1.5 -206 -1.5 169
Moneyline +119 -143
Total Over 6.5 (-115) Under 6.5 (-105)
Where Yankee Stadium, Bronx, New York
When Friday, September 25, 2026
Time 04:05 PM EDT
TV MLB.TV
The Baltimore Orioles and New York Yankees meet Friday in MLB action at Yankee Stadium. Here’s a Baltimore Orioles vs. New York Yankees Prediction. This article will include a Baltimore Orioles vs. New York Yankees Pick.

Baltimore Orioles Betting Preview


The Baltimore Orioles are 78-81 on the year. The Baltimore Orioles are batting .233 on the season and have a .313 OBP and a .394 slugging percentage. The Baltimore Orioles pitching staff has a 4.08 ERA and a 1.34 WHIP. Pete Alonso leads the Baltimore Orioles with 157 hits and 110 RBI, while Gunnar Henderson and Leody Taveras have combined for 231 hits and 113 RBI.

Trevor Rogers gets the ball for the Baltimore Orioles, and he is 10-11 with a 4.07 ERA and 153 strikeouts this season. Rogers is 1-2 with a 6.41 ERA and 21 strikeouts in his career against the New York Yankees.

New York Yankees Betting Preview


The New York Yankees are 92-67 this year. The New York Yankees are batting .234 on the season, with a .311 OBP and a .410 slugging percentage. The New York Yankees’ pitching staff has a 3.20 ERA and a 1.16 WHIP. Ben Rice leads the New York Yankees with 148 hits and 97 RBI, while Cody Bellinger and Jazz Chisholm Jr. have combined for 240 hits and 128 RBI.

Brendan Beck gets the ball for the New York Yankees, and he is 0-1 with an 8.22 ERA and 5 strikeouts this season. This will be Beck’s first career game against the Baltimore Orioles.

Why the New York Yankees will win

Why the Baltimore Orioles will win

Total Runs Facts

New York Yankees Player Prop Facts

Baltimore Orioles Player Prop Facts

Matchup/League Facts

Baltimore Orioles vs New York Yankees Prediction


The Yankees are obviously the better team and have a track record of being the Orioles’ daddy. However, I’m not excited about Beck and his 7.2-inning sample size. Rogers has shown flashes of returning to a ptoetial all star and that includes allowing 22 hits and 8 runs in his last 28 innings. In July, Rogers allowed 28 hits and 8 earned runs in 30.1 innings. Rogers has been a bright spot for the O’s this season. This game isn’t that important for the Yanks, who have already clinched. I’ll take the plus money with the more trustworthy arm.

Randy Chambers's Pick: Baltimore Orioles

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