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Baltimore Orioles vs Los Angeles Angels Prediction 6/22/2026 Today’s MLB Picks

May 8, 2026; Baltimore, Maryland, USA; Baltimore Orioles pitcher Kyle Bradish (38) during the first inning against the Athletics at Oriole Park at Camden Yards. Mandatory Credit: Daniel Kucin Jr.-Imagn Images

May 8, 2026; Baltimore, Maryland, USA; Baltimore Orioles pitcher Kyle Bradish (38) during the first inning against the Athletics at Oriole Park at Camden Yards. Mandatory Credit: Daniel Kucin Jr.-Imagn Images

MATCHUP Baltimore Orioles Los Angeles Angels
Team Records 37-42 32-47
Spread -1.5 101 +1.5 -122
Moneyline -163 +135
Total Over 9 (-105) Under 9 (-114)
Where Angel Stadium, Anaheim, California
When Monday, June 22, 2026
Time 09:38 PM EDT
TV MLB.TV

In this article, we will formulate a Orioles vs Angels Prediction for this MLB matchup on Monday, June 22nd in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Angels Preview

The Los Angeles Angels have a 32-47 record this season and are sitting in the 5th place of the AL West. They have a 17-20 home record and are coming off a 9-7 road win against the Athletics. They will face the Athletics and the Mariners next.

The Angels have a .240 batting average this season, .320 OBP and .401 Slugging percentage. Los Angeles’s pitching staff has a 4.65 ERA and 1.43 WHIP. Nolan Schanuel is the team’s best hitter with a .258 batting average. Jo Adell leads the team in RBI with 41, while Mike Trout adds a team-high 17 home runs.

Sam Aldegheri (L) is the projected starting pitcher for the Angels, and he has a 2-2 record, 4.50 ERA and 1.55 WHIP.

Baltimore Orioles Preview

The Baltimore Orioles have a 37-42 record this season and are sitting in the 4th place of the AL East. They have a 15-23 road record and are coming off a 12-1 road win against the Dodgers. They will face the Nationals and the White Sox next.

The Orioles have a .241 batting average this season, .321 OBP and .403 Slugging percentage. Baltimore’s pitching staff has a 4.45 ERA and 1.39 WHIP. Taylor Ward is the team’s best hitter with a .255 batting average. Pete Alonso leads the team in RBI with 52, adding a team-high 18 home runs.

Kyle Bradish (R) is the projected starting pitcher for the Orioles, and he has a 4-7 record, 4.00 ERA and 1.51 WHIP.

Baltimore Orioles @ Los Angeles Angels Betting Trends: June 22, 2026

Why the Los Angeles Angels will win

Why the Baltimore Orioles will win

Total Runs Facts

Los Angeles Angels Player Prop Facts

Baltimore Orioles Player Prop Facts

Matchup/League Facts

Orioles vs Angels Prediction

The Orioles are 6-1 in their last 7 meetings against the Angels and are 3-1 in their last 4 visits in Los Angeles.

In this Orioles vs Angels Prediction, the Orioles are coming as -180 road favorites. I don’t get why the Orioles are being so big favorites on the road with Bradish on the mound and his 1.50+ WHIP. He has been weaker on the road with a 5+ ERA and the Orioles have been weaker against lefties, while facing Sam Aldegheri who sits on a 1.76 home ERA. Take the Angels to win at home for plus money.

Nikos Lagouretos's Pick: Los Angeles Angels ML

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