Astros vs Guardians Prediction 6/7/25 MLB Picks

In this article, we will formulate an Astros vs Guardians prediction for this MLB game on Saturday, June 7th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Houston Astros Betting Preview

The Houston Astros are 35-28 this year after they won game one in this series by a score of 4-2. Houston scored four runs in the fifth/sixth innings and was able to pitch very well in the late innings for the win. The Astros recorded 10 hits in the game, and they were led by Walker, who went 1-4 with two RBIs in the win. Houston started Gordon, who allowed seven hits and one earned run over 5.0 innings for the win, while Hader picked up the save. 

Prior to this series, the Astros won two out of three against the Pirates and split four games with the Rays. Houston has won four of their last five games, and they are currently first in the AL West standings. The Houston pitching staff has a 3.54 ERA with a 1.16 WHIP and a .220 opponent batting average, while their offense has scored 254 runs with a .253 batting average and a .319 on-base percentage this season. Isaac Paredes has led Houston with 14 home runs and 37 RBIs, while Jeremy Pena has added nine home runs and 31 RBIs this year. The projected starting pitcher for Houston is Hunter Brown, who is 8-3 with a 1.83 ERA and a 0.91 WHIP over 73.2 innings pitched this year. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 33-29 this season after they dropped game one in this series on Friday night. Cleveland cut the deficit to 3-1 and 4-2, but couldn’t get any closer in the loss. The Guardians recorded nine hits in the game, and they were led by Fry and Wilson, who both had one RBI in the loss. Cleveland started Allen, who allowed seven hits and four earned runs over 6.0 innings for the loss, while Festa, Herrin, and Enright pitched the final three innings. 

Prior to this series, the Guardians lost two out of three against the Yankees, but did win two out of three against the Angels before that. Cleveland has lost three of their last four games, and they are currently third in the AL Central standings. The Cleveland pitching staff has a 3.99 ERA with a 1.38 WHIP and a .253 opponent batting average, while the offense has scored 243 runs with a .234 batting average and a .305 on-base percentage this season. Jose Ramirez has led Cleveland with 11 home runs and 29 RBIs, while Kyle Manzardo has also added 11 home runs and 29 RBIs this year. The projected starting pitcher for Cleveland is Gavin Williams, who is 5-3 with a 3.79 ERA and a 1.45 WHIP over 59.1 innings pitched this season. 

Why the Guardians will beat the Astros 

• The Astros have lost six of their last seven games as road favorites following a win.
• The Guardians have won eight of their last nine day games against AL West opponents.
• The Guardians have covered the run line in each of their last nine Saturday day home games against American League opponents.
• The Astros have failed to cover the run line in each of their last four day games against AL Central opponents following a win.
• The Astros have trailed after 5 innings in three of their last four day games against American League opponents.

Why the Astros will beat the Guardians 

• The Astros have won each of their last four games against the Guardians.
• The Guardians have lost five of their last six home games against teams that held a winning record.
• The Astros have covered the run line in seven of their last eight road games against AL Central opponents that held a winning record.
• The Guardians have failed to cover the run line in five of their last six games at Progressive Field against teams that held a winning record.
• The Astros have led after 5 innings in five of their last six games at Progressive Field.

Total Runs Facts

• Seven of the Guardians’ last eight games against American League opponents have gone UNDER the total runs line.
• Five of the Astros’ last six road games against American League opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Astros’ last eight Saturday day games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Guardians’ last eight games against American League opponents.

Astros vs Guardians Prediction 

Houston was able to overcome a late arrival in Cleveland after their game on Thursday to pick up the win in game one, and they have won four of their last five games. The Astros are 13-16 on the road this year, while the Guardians are 17-12 at home. Cleveland has scored two runs or fewer in three of their last four games, and they will go against Brown, who has allowed one earned run or fewer in four of his last five starts. The Astros will face Williams, who has allowed two earned runs or fewer in four of his last five. I like how both of these pitchers have looked recently, and I think runs are going to be hard to come by. Take the under here.