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Arizona Diamondbacks vs St. Louis Cardinals Prediction 5/24/25 MLB Picks

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St. Louis Cardinals (28-23) vs Arizona Diamondbacks (26-25)

Game Info: Saturday, May 24, 2025 at 2:15 pm (Busch Stadium)

The Line: Betting Odds: St. Louis Cardinals -115 / Arizona Diamondbacks -105 — Over/Under: 8

(Get latest betting odds)

The Arizona Diamondbacks and St. Louis Cardinals meet Saturday in MLB action at Busch Stadium. Here’s a Arizona Diamondbacks vs St. Louis Cardinals Prediction. This article will include a Arizona Diamondbacks vs St. Louis Cardinals Pick.

Arizona Diamondbacks Betting Preview

The Arizona Diamondbacks are 26-25 on the year and play the Pirates, Nationals, and Braves next. The Arizona Diamondbacks are batting .253 on the season, have a .333 OBP, and a .447 slugging percentage. The Arizona Diamondbacks pitching staff has a 4.64 ERA and a 1.32 WHIP. Corbin Carroll leads the Arizona Diamondbacks with 58 hits and 34 RBI, while Josh Naylor and Geraldo Perdomo have combined for 107 hits and 66 RBI. 

Merrill Kelly gets the ball for the Arizona Diamondbacks, and he is 5-2 with a 3.26 ERA and 52 strikeouts this season. Kelly is 3-1 with a 2.75 ERA and 30 strikeouts in his career against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 28-23 on the year and play the Orioles, Rangers, and Royals next. The St. Louis Cardinals are batting .262 on the season, have a .334 OBP, and a .401 slugging percentage. The St. Louis Cardinals pitching staff has a 3.72 ERA and a 1.21 WHIP. Brendan Donovan leads the St. Louis Cardinals with 61 hits and 22 RBI while Lars Nootbaar and Willson Contreras have combined for 94 hits and 53 RBI.

Matthew Liberatore gets the ball for the St. Louis Cardinals, and he is 3-3 with a 2.92 ERA and 47 strikeouts this season. This will be Liberatore’s first career game against the Arizona Diamondbacks.

Why the St. Louis Cardinals will win

Why the Arizona Diamondbacks will win

St. Louis Cardinals Player Prop Facts

Arizona Diamondbacks Player Prop Facts

Arizona Diamondbacks vs St. Louis Cardinals Prediction

The Diamondbacks are in a funk offensively and the Cardinals have been hit or miss lately. Kelly has been on fire, allowing 19 hits and five runs in his last 25.1 innings. Kelly has allowed eight runs in his last 37 innings. Liberatore has allowed 18 hits and six runs in his last 21.1 innings. Liberatore has a 1.80 ERA and .189 allowed batting average in 25 home innings. This feels like a low scoring game with two pitchers who are in fantastic form. Give me the under.

Randy Chambers's Pick: Under 8

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