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South Florida vs East Carolina Prediction 11/6/2026 Today’s College Football Picks

Sep 12, 2026; West Point, New York, USA;  South Florida Bulls quarterback Michael Van Buren Jr. (3) celebrates his touchdown against the Army Black Knights during the second half at Michie Stadium.  Mandatory Credit: Danny Wild-Imagn Images

Sep 12, 2026; West Point, New York, USA; South Florida Bulls quarterback Michael Van Buren Jr. (3) celebrates his touchdown against the Army Black Knights during the second half at Michie Stadium. Mandatory Credit: Danny Wild-Imagn Images

South Florida vs East Carolina Odds and Matchup Info
MATCHUP South Florida Bulls East Carolina Pirates
Team Records 6-2 4-4
Spread +1.5 -108 -1.5 -112
Moneyline +105 -125
Total Over 39.5 (-108) Under 39.5 (-112)
Where Dowdy-Ficklen Stadium, Greenville, NC
When Friday, November 6, 2026
Time 07:30 PM EST
TV ESPN2

South Florida vs East Carolina Prediction

In this South Florida vs East Carolina prediction, East Carolina is coming as -2.5 home favorites. South Florida has a better record this season and have back-to-back wins where they played excellent defense, holding their opponents into just 12 points combined. They will face an East Carolina squad that has lost two of its last three games but has three consecutive home wins but have been weaker both offensively and defensively, so the road dog is barking in this matchup. South Florida has the 14th-best defense in the entire country and a +12.5 point differential and have been excellent in managing turnovers, averaging just 0.5 per game, so I expect them to force close game today or even win outright. Take South Florida and grab the +2.5 points.

East Carolina Pirates Preview

East Carolina has a 4-4 record and a 2-2 record in the American. They are coming off a 17-9 home win against Temple and will face Charlotte and Army next.

Offensively, East Carolina averages 24 points per game, ranking 94th in the nation, while defensively, they allow 24.1 points per game, which is 64th. East Carolina averages 351.0 total yards per game (186.5 passing and 164.5 rushing), while allowing 336.4 total yards per game (139.8 rushing and 196.6 passing). They average 68.1 plays per game and 5.2 yards per play on offense, while allowing 68.8 plays per game and 4.9 yards per play on defense. East Carolina averages 18.1 first downs per game on offense and 18.8 first downs per game on defense. They have turned the ball over 1.8 times per game and are forcing 1.5 turnovers per game.

Mitch Griffis leads East Carolina with 753 passing yards with 54.8% completed passes and 4 touchdowns. TJ Engleman Jr. leads the team in rushing yards with 689, while Ray Ray Joseph has a team-high 303 receiving yards and 33 receptions. Defensively, DJ Johnson Jr. has a team-high 56 total tackles (24 of them solo), while Jasiyah Robinson and Preston Carr are tied for the team lead with 2.5 sacks.

No Injuries to Report for East Carolina

South Florida Bulls Preview

South Florida has a 6-2 record and a 2-2 record in the American. They are coming off a 30-10 home win against UAB and will face Memphis and Florida Atlantic next.

Offensively, South Florida averages 27.0 points per game, ranking 76th in the nation, while defensively, they allow 14.5 points per game, which is 10th. South Florida averages 314.6 total yards per game (166.6 passing and 148.0 rushing), while allowing 306.6 total yards per game (128.3 rushing and 178.4 passing). They average 58.9 plays per game and 5.3 yards per play on offense, while allowing 63.8 plays per game and 4.8 yards per play on defense. South Florida averages 18.6 first downs per game on offense and 17.0 first downs per game on defense. They have turned the ball over 0.5 times per game and are forcing 1.1 turnovers per game.

Michael Van Buren Jr. leads South Florida with 1,273 passing yards with 64.1% completed passes and 6 touchdowns. D.J. Crowther leads the team in rushing yards with 578, while Bryson Rodgers has a team-high 345 receiving yards and 33 receptions. Defensively, Ayden Jackson has a team-high 42 total tackles (27 of them solo), while C.J. Hicks leads the team with 5.0 sacks.

Injury Report

·        A. Branch            WR         Questionable – Undisclosed          Oct 18, ’26

·        J. Alexis WR         Questionable – Undisclosed          Oct 18, ’26

South Florida Bulls @ East Carolina Pirates Betting Trends: Week 10

 

Why the East Carolina Pirates will win

Why the South Florida Bulls will win

Total Points Facts

East Carolina Pirates Player Prop Facts

South Florida Bulls Player Prop Facts

Matchup/League Facts

Nikos Lagouretos's Pick: South Florida +2.5

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