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Iowa vs Michigan Prediction 9/26/2026 Today’s College Football Picks

Sep 19, 2026; Ann Arbor, Michigan, USA;  Michigan Wolverines quarterback Tommy Carr (14) makes a throw against the Texas El Paso Miners during the fourth quarter at Michigan Stadium.  Mandatory Credit: Rick Osentoski-Imagn Images

Sep 19, 2026; Ann Arbor, Michigan, USA; Michigan Wolverines quarterback Tommy Carr (14) makes a throw against the Texas El Paso Miners during the fourth quarter at Michigan Stadium. Mandatory Credit: Rick Osentoski-Imagn Images

MATCHUP Iowa Hawkeyes Michigan Wolverines
Team Records 3-0 3-0
Spread +5.5 -110 -5.5 -110
Moneyline +180 -218
Total Over 38.5 (-112) Under 38.5 (-108)
Where Michigan Stadium, Ann Arbor, MI
When Saturday, September 26, 2026
Time 03:30 PM EDT
TV CBS
In this article, we will formulate an Iowa vs Michigan Prediction for this College Football Week 4 matchup on Saturday, September 26th. Let’s take a look at the prediction for this College Football matchup.

Michigan Wolverines Preview


Michigan has a 3-0 record and are coming off a 52-17 home win against UTEP. They will face Minnesota and Penn State next. Offensively, Michigan averages 27.3 points per game, ranking 94th in the nation, while defensively, they allow 13 points per game, which is 14th. Michigan averages 323.3 total yards per game (175.7 passing and 147.7 rushing), while allowing 220 total yards per game (96.3 rushing and 123.7 passing).

Bryce Underwood leads Michigan with 504 passing yards with 62.5% completed passes and 3 touchdowns. Bryce Underwood leads the team in rushing yards with 156, while JJ Buchanan has a team-high 15 receptions for 266 receiving yards. Defensively, Troy Bowles has a team-high 25 total tackles (13 of them solo), while John Henry Daley leads the team with 2.5 sacks.

Iowa Hawkeyes Preview


Iowa has a 3-0 record and are coming off a 55-0 home win against Northern Iowa. They will face Ohio State and Washington next. Offensively, Iowa averages 37 points per game, ranking 47th in the nation, while defensively, they allow 4.3 points per game, which is 1st. Iowa averages 477 total yards per game (209 passing and 268 rushing), while allowing 176.7 total yards per game (66 rushing and 110.7 passing).

Hank Brown leads Iowa with 473 passing yards with 72.6% completed passes and 3 touchdowns. Kamari Moulton leads the team in rushing yards with 240, while Tony Diaz has a team-high 17 receptions for 201 receiving yards. Defensively, Cam Buffington has a team-high 27 total tackles (17 of them solo), while Joseph Anderson leads the team with 2 sacks.

Iowa Hawkeyes @ Michigan Wolverines Betting Trends: Week 4


Why the Michigan Wolverines will win

Why the Iowa Hawkeyes will win

Total Points Facts

Michigan Wolverines Player Prop Facts

Iowa Hawkeyes Player Prop Facts

Matchup/League Facts

Iowa vs Michigan Prediction


In this Iowa vs Michigan Prediction, Michigan is coming as -5.5 home favorites. Both teams have been undefeated this season and both rank on the top-20 of the country thus far. Michigan has covered the spread in two of its three games, but almost falls out of the top-100 offensively, while Iowa has been better on both sides of the court, with a top-50 offense and the best defense in the nation but will be tested for the first time on the road. Michigan has been dominating Iowa in recent years, having won their last four meetings and are 6-1 ATS in their last 7 meetings, so I trust them to win and cover the -5.5 spread at home in this one.

 

Nikos Lagouretos's Pick: Michigan -5.5

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