Missouri vs Kansas Prediction 9/11/2026 Today’s College Football Picks
Chris Ruffolo
Sep 3, 2026; Columbia, Missouri, USA; Missouri Tigers quarterback Austin Simmons (13) throws a pass against the Arkansas-Pine Bluff Golden Lions during the first half at Faurot Field at Memorial Stadium. Mandatory Credit: Denny Medley-Imagn Images
MATCHUP
Missouri Tigers
Kansas Jayhawks
Team Records
1-0
1-0
Spread
-5.5 -108
+5.5 -112
Moneyline
-205
+170
Total
Over 50.5 (-115)
Under 50.5 (-105)
Where
David Booth Kansas Memorial Stadium, Lawrence, KS
When
Friday, September 11, 2026
Time
08:00 PM EDT
TV
FOX
The Missouri Tigers and the Kansas Jayhawks meet in week 2 college football action from David Booth Memorial Stadium on Friday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Missouri Tigers vs. Kansas Jayhawks Prediction.
Missouri Tigers Recap
The Missouri Tigers come into this game looking to add on to their 54-14 win over Arkansas Pine Bluff last time out to start the year at 1-0. After this game, Missouri will head home for a game against Troy.
Tigers Looking For Big Road Rivalry Win
Austin Simmons threw for 252 yards and 4 TDs on 17 of 19 passing while Matt Zollers added 87 yards on 8 of 12 passing and rushed for 26 yards and a score. Jamal Roberts rushed for 47 yards and a TD on 13 carries while Xai’Shaun Edwards added 45 rushing yards and Preston Hatfield chipped in 34 yards and a touchdown. Donovan Olugbode had a team-high 107 receiving yards and 2 TDs on 7 catches while Cayden Lee added 5 catches for 89 yards and a touchdown. Shaun Terry II added 55 receiving yards and a TD while Naeshaun Montgomery chipped in 3 catches for 47 yards. On defense, Jeremiah Beasley had a team-high 7 total tackles to lead Missouri’s defense, while Jason Dowell recorded 2 total tackles, a tackle for loss, and the team’s only sack.
Kansas Jayhawks Recap
The Kansas Jayhawks come into this game looking to add on to their 51-6 win over LIU last time out to start the year at 1-0. After this game, Kansas will take on Arizona state in a matchup at home.
Jayhawks Hoping To Emerge Victorious As Home Dog
Isaiah Marshall threw for 246 yards and 2 TDs on 14 of 19 passing while also rushing for 49 yards, and Cole Ballard added 90 yards on 4 of 6 passing. Yasin Willis led the ground game with 72 rushing yards and 2 TDs on 11 carries while Micah Johnson added 52 yards and a TD on 11 carries and Jalen Dupree chipped in 35 yards and a score. Nik McMillan had a team-high 130 receiving yards and a TD on 6 catches while Bryson Hayes added 2 catches for 56 yards and Tate Nagy chipped in 3 catches for 40 yards and a touchdown. On defense, Quincy Davis had a team-high 5 total tackles to lead Kansas’ defense, while Leroy Harris III logged 4 total tackles and a team-high 4 tackles for loss.
Kansas has won each of its last eight games against non-conference opponents at David Booth Kansas Memorial Stadium.
Missouri has lost four of its last five games as an AP-ranked team.
The team ranked 23rd in the AP Poll has failed to cover the spread in eight of its last nine games.
Kansas has covered the spread in five of its last six games as a home underdog.
Kansas has won the first quarter in each of its last six home games against non-conference opponents.
Kansas has won the first half in each of its last 10 home games against non-conference opponents.
Why the Missouri Tigers will win
Missouri has won each of its last 25 games against non-AP-ranked teams.
Kansas has lost eight of its last nine September games as a home underdog.
Missouri has covered the spread in each of its last eight road games against non-AP-ranked teams.
Kansas has failed to cover the spread in each of its last four games against teams from Missouri.
The team ranked 23rd in the AP Poll has won the first quarter in each of its last four games.
Kansas has lost the first half in eight of its last nine September games as a home underdog.
Total Points Facts
Each of Kansas’ last seven September games as a home underdog have gone OVER the total points line.
Each of Missouri’s last four road games have gone UNDER the total points line.
Kansas Jayhawks Player Prop Facts
Nik McMillan has recorded 100+ receiving yards in seven consecutive games – longest streak in the FBS, heading into Week 2.
Missouri Tigers Player Prop Facts
Heading into Week 2, Brett Norfleet ranks T1st amongst qualified players for catch rate (100.0%) this season.
Matchup/League Facts
Kansas ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
Kansas ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).
Missouri ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
Missouri ranks T1st among FBS teams for Q2 opponent points per game this season (0.0).
Missouri Tigers vs. Kansas Jayhawks Prediction
I’m on Kansas and the points. This is a rivalry game plain and simple and getting Kansas as a home dog I think is where it’s at. The Jayhawks have their issues, and it’s hard to really get a read on either team after blowing out inferior competition in week 1, but in this spot, I want the points with KU.