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Los Angeles Kings vs St. Louis Blues Prediction 10/21/2025 Today’s NHL Picks

Mar 8, 2025; Los Angeles, California, USA; Los Angeles Kings left wing Andrei Kuzmenko (96) looks to shoot ahead of St. Louis Blues defenseman Ryan Suter (22) and goaltender Joel Hofer (30) during the second period at Crypto.com Arena. Mandatory Credit: Ryan Sun-Imagn Images

Mar 8, 2025; Los Angeles, California, USA; Los Angeles Kings left wing Andrei Kuzmenko (96) looks to shoot ahead of St. Louis Blues defenseman Ryan Suter (22) and goaltender Joel Hofer (30) during the second period at Crypto.com Arena. Mandatory Credit: Ryan Sun-Imagn Images

Los Angeles (1-3-2) vs St. Louis (3-2-0)

October 21, 2025 at 08:00 PM EDT

The Line: Betting Odds: St. Louis -1.5 — Over/Under: +5.5

(Get latest betting odds)

In this article, we will formulate a Kings vs Blues Prediction for this NHL game on Tuesday, October 21st. Let’s take a look at the prediction for this NHL matchup.

St. Louis Blues Preview

The Blues have 6 points this season with a 3-2 record, and are 3-2 ATS and 3-2 in over/under. They have a 1-2 home record and a 2-0 road record and are sitting 5th in the Central Division. They are coming off a 3-1 home win over the Stars and will face the Utah Mammoth, Red Wings and Penguins next. Offensively, the Blues are averaging 3.00 goals per game and are scoring 15.38% of their power play opportunities. Defensively, they are allowing 3.60 goals per game and are killing 80% of their opponent’s power plays.

Jake Neighbours leads St. Louis with 5 points, 4 goals and one assist, while Pavel Buchnevich follows with 4 points and 4 assists. Jordan Binnington is the starting goalie for the Blues, and he has a 2-1 record, with 2.81 GAA and .882 SV%. Joel Hofer is the backup goalie and he has a 1-1 record, with 5.01 GAA and .824 SV%.

Los Angeles Kings Preview

The Kings have 4 points this season with a 1-3-2 record, and are 4-2 ATS and 3-2 in over/under. They have a 0-2-1 home record and a 1-1-1 road record and are sitting 6th in the Pacific Division. They are coming off a 3-4 home loss over the Hurricanes and will face the Stars, Predators and Blackhawks next. Offensively, the Kings are averaging 2.67 goals per game and are scoring 25.00% of their power play opportunities. Defensively, they are allowing 3.83 goals per game and are killing 70.37% of their opponent’s power plays.

Adrian Kempe leads Los Angeles with 7 points, 2 goals and 5 assists, while Quinton Byfield follows with 6 points, 2 goals and 4 assists. Darcy Kuemper is the starting goalie and he has a 0-2-1 record, with 3.35 GAA and .868 SV%. Anton Forsberg is the backup goalie for the Kings, and he has a 1-1-1 record, with 3.89 GAA and .880 SV%.

Los Angeles Kings @ St. Louis Blues Betting Trends: October 21, 2025

Why the St. Louis Blues will win

  • The Blues have won each of their last seven home games following a home win.
  • The Kings have lost nine of their last 10 games.
  • The Blues have covered the puck line in each of their last five games against the Kings.
  • The Kings have failed to cover the puck line in five of their last six games at Enterprise Center.
  • The Kings have lost the third period in each of their last seven games after coming off overtime.

Why the Los Angeles Kings will win

  • The underdogs have won each of the Blues’ last six games at Enterprise Center.
  • The Blues have lost each of their last five night games following a win.
  • The underdogs have covered the puck line in each of the Blues’ last six games at Enterprise Center.
  • The Blues have failed to cover the puck line in each of their last four games as favorites following a win.
  • The underdogs have won the second period in each of the Blues’ last five games at Enterprise Center.

Total Goals Facts

  • Each of the Blues’ last six games against Pacific Division opponents have gone OVER the total goals line.
  • Six of the Kings’ last seven road games have gone OVER the total goals line.
  • The ‘Over 1.5 Goals Period 2′ market has hit in each of the Kings’ last 11 games as underdogs.
  • The ‘Over 1.5 Goals Period 2′ market has hit in each of the Blues’ last nine games.

St. Louis Blues Player Prop Facts

  • Jordan Kyrou has scored at least one goal in each of the Blues’ last six Tuesday games.
  • Dylan Holloway has recorded at least one assist in seven of the Blues’ last eight home games against Pacific Division opponents.
  • Dylan Holloway has recorded at least one point in each of the Blues’ last eight home games against Pacific Division opponents.
  • Jake Neighbours ranks 1st amongst qualified players for shooting percentage (50.0%) this season.

Los Angeles Kings Player Prop Facts

  • Kevin Fiala has scored at least one goal in four of the Kings’ last five games against Central Division opponents.
  • Anze Kopitar has recorded a point in each of his last six appearances.
  • Anze Kopitar has recorded an assist in each of his last eight Tuesday appearances.
  • Adrian Kempe ranks T1st in the league for shootout goals (1) this season.

Matchup/League Facts

  • The St. Louis Blues rank T25th in the league for goals against per game this season (3.60).
  • The St. Louis Blues have suffered the equal-largest margin of defeat in the NHL this season (5-goals vs Wild on October, 9).
  • The Los Angeles Kings rank 29th in the league for goals against per game this season (3.83).
  • The Los Angeles Kings rank 27th in the league in penalty kill percentage this season (70.37%).

Kings vs Blues Prediction

The Blues were 2-1 in their three meetings against the Kings last season, winning their only meeting in Saint Louis by 4-1. They are 4-1 in their last 5 meetings, and have won their last three meetings in Saint Louis.

In this Kings vs Blues Prediction, the Blues are coming as -122 home favorites. The Kings are having a rough start to the season, having just one win in six games played, and are coming off four consecutive losses. On the flip side, the Blues are 3-1 in their last 4 games, and are better both offensively and defensively. Kuemper is also struggling mightily between the pipes for LA, so I like the home team in this matchup. Take the St. Louis Blues on the moneyline in this one.

Nikos Lagouretos's Pick: St. Louis Blues ML

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