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Golden Knights vs Blues Prediction 10/22/2026 Today’s NHL Picks

Oct 20, 2026; Las Vegas, Nevada, USA;  Vegas Golden Knights head coach Ryan Craig looks on in the third period of the game against the against the Tampa Bay Lightning at T-Mobile Arena.  Mandatory Credit: Candice Ward-Imagn Images

Oct 20, 2026; Las Vegas, Nevada, USA; Vegas Golden Knights head coach Ryan Craig looks on in the third period of the game against the against the Tampa Bay Lightning at T-Mobile Arena. Mandatory Credit: Candice Ward-Imagn Images

Vegas vs St. Louis Odds and Matchup Info
MATCHUP Vegas Golden Knights St. Louis Blues
Team Records 8-3 4-4
Spread -1.5 210 +1.5 -258
Moneyline -125 +105
Total Over 6.5 (114) Under 6.5 (-135)
Where Enterprise Center, St. Louis, MO
When Thursday, October 22, 2026
Time 08:00 PM EDT
TV ESPN+

The Vegas Golden Knights and St. Louis Blues meet Thursday in NHL action at the Enterprise Center. Here’s a Golden Knights vs. Blues Prediction. This article will include a Golden Knights vs. Blues Pick.

Vegas Golden Knights Betting Preview

The Vegas Golden Knights beat the Penguins, lost to the Lightning, and they play the Blue Jackets next. The Golden Knights have won 7 of their last 9 games.

The Vegas Golden Knights are averaging 3.91 goals per game and are scoring on 25 percent of their power play opportunities. Mark Stone leads Vegas with 8 goals, Jack Eichel has 13 assists, and Mitch Marner has 28 shots on goal. Defensively, the Vegas Golden Knights are allowing 2.73 goals per game and are killing 73.1 percent of their opponent’s power plays. Carter Hart has allowed 20 goals on 178 shots, and Adin Hill has allowed 9 goals on 96 shots.

St. Louis Blues Betting Preview

The St. Louis Blues lost to the Predators, beat the Jets, and they play the Hurricanes next. The Blues have lost 5 of their last 8 games.

The St. Louis Blues are averaging 3.22 goals per game and are scoring on 19.2 percent of their power play opportunities. Mason McTavish leads St. Louis with 5 goals; Dylan Holloway has 6 assists; and Jimmy Snuggerud has 22 shots on goal. Defensively, the St. Louis Blues are allowing 3.22 goals per game and are killing 85.7 percent of their opponent’s power plays. Joel Hofer has allowed 13 goals on 161 shots faced, and Jordan Binnington has given up 14 goals on 83 shots.

Golden Knights vs Blues Injury Report

The Blues will be without Ross Johnston, Torey Krug, Dillon Dube, Alexey Toropchenko, Tyler Tucker, Felix Trudeau, and Logan Mailloux.

The Golden Knights will be without Parker Wotherspoon.

Golden Knights vs Blues Prediction

We’re getting a low price with a Golden Knights side that’s been one of the most impressive teams in the league up to this point. The Golden Knights have also won 7 of the last 10 games against the Blues. The Blues have games here and there where they can’t keep the puck out of the net, and they’re one of the most banged-up teams in the league. At this price, the Golden Knights are hard to turn down on Thursday night.

Randy Chambers's Pick: Golden Knights

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