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Florida Panthers vs Tampa Bay Lightning Prediction 4/22/25 NHL Picks

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Tampa Bay Lightning (47-27-8) vs Florida Panthers (47-31-4)

Game Info: Tuesday, April 22, 2025 at 8:30 pm (Amalie Arena)

The Line: Betting Odds: Tampa Bay Lightning -115 / Florida Panthers -105 — Over/Under: 5.5

(Get latest betting odds)

The Florida Panthers and the Tampa Bay Lightning meet Tuesday in NHL action from Amalie Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Florida Panthers vs. Tampa Bay Lightning prediction.

Matchup History

These two teams split the regular season meetings 2-2, with the road team winning the first two meetings in a home-and-home in late December, with the Panthers winning 4-2 in Tampa Bay on December 22nd, 2024, before the Lightning got their revenge the next night, 4-0 in Sunrise. Florida then won 2-1 at home on March 3rd, 2025 before the Bolts won 5-1 in Tampa Bay on April 15th, 2025.

Florida Panthers Recap

The Florida Panthers come into the series as the 3-seed in the Atlantic division, finishing the year with an overall record of 47-31-4.

Panthers Begin Stanley Cup Title Defense

Sam Reinhart has a team-high 81 points including 39 goals and 42 assists while Sam Bennett has 51 points with 25 goals and 26 assists and Anton Lundell has 45 points of his own with 17 goals and 28 assists. Aleksander Barkov also has 71 points with 51 assists of his own while Carter Verhaeghe has 53 points with 20 goals and 33 assists and Matthew Tkachuk has 57 points with 22 goals and 35 assists. Sergei Bobrovsky is 33-19-2 with a 2.44 GAA and a .906 save percentage in goal for Florida this season. Vitek Vanecek is also 2-4-1 with a 3.00 GAA and an .890 save percentage in goal for the Panthers this year.

Why the Florida Panthers will win

Florida Panthers Player Prop Facts

Tampa Bay Lightning Recap

The Tampa Bay Lightning come into this series as the 2-seed in the Atlantic division after finishing the regular season with an overall record of 47-27-8 on the year.

Lightning Trying To Snap Run Of Back-To-Back First Round Exits

Nikita Kucherov leads the Bolts with 121 points including a team-high 37 goals and 84 assists while Brandon Hagel has 90 points with 35 goals and 55 assists and Anthony Cirelli has 59 points of his own with 27 goals and 32 assists. Brayden Point has 82 points with 42 goals and 40 assists while Victor Hedman has 66 points with 51 assists. Jake Guentzel also has 80 points with 41 goals and 39 assists. Andrei Vasilevskiy has gone 38-20-5 with a 2.18 GAA and a .921 save percentage while Jonas Johansson has gone 9-6-3 with a 3.13 GAA and an .895 save percentage on the year in goal for Tampa Bay.

Why the Tampa Bay Lightning will win

Tampa Bay Lightning Player Prop Facts

Total Goals Facts

Florida Panthers vs. Tampa Bay Lightning Prediction

I’m on the Lightning here. The Panthers didn’t have the best run of form down the stretch, and while they are the defending Stanley Cup champs, this is going to be a tough series to try to turn things around. Tampa Bay is one of the toughest road environments for opposing teams in the NHL, especially when the rival Panthers come to town. This is a series I see going six or seven games, but I think the Lightning draw first blood here. Give me the Bolts.

Chris Ruffolo's Pick: Tampa Bay Lightning -115

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