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Florida Panthers vs Ottawa Senators Prediction 10/21/2026 Today’s NHL Picks

Oct 17, 2026; Sunrise, Florida, USA;  Florida Panthers left wing Matthew Tkachuk (19), left wing Brady Tkachuk (8), center Sam Reinhart (13), and defenseman Seth Jones (3) celebrate goal during the third period against the Seattle Kraken at Amerant Bank Arena.  Mandatory Credit: Isabella Frias-Imagn Images

Oct 17, 2026; Sunrise, Florida, USA; Florida Panthers left wing Matthew Tkachuk (19), left wing Brady Tkachuk (8), center Sam Reinhart (13), and defenseman Seth Jones (3) celebrate goal during the third period against the Seattle Kraken at Amerant Bank Arena. Mandatory Credit: Isabella Frias-Imagn Images

Florida vs Ottawa Odds and Matchup Info
MATCHUP Florida Panthers Ottawa Senators
Team Records 5-2 6-3
Spread +1.5 -278 -1.5 225
Moneyline -112 -108
Total Over 5.5 (-125) Under 5.5 (105)
Where Canadian Tire Centre, Ottawa, ON
When Wednesday, October 21, 2026
Time 07:30 PM EDT
TV ESPN+
The Florida Panthers and Ottawa Senators meet Wednesday in NHL action at the Canadian Tire Centre. Here’s a Florida Panthers vs. Ottawa Senators Prediction. This article will include a Florida Panthers vs. Ottawa Senators Pick.

Florida Panthers Betting Preview


The Florida Panthers beat the Canucks and Kraken, and they play the Penguins next. The Panthers have won 3 straight games.

The Florida Panthers are averaging 3.33 goals per game and are scoring on 20.9 percent of their power-play opportunities. Brady Tkachuk leads Florida with 6 goals, Matthew Tkachuk has 11 assists, and Sam Reinhart has 29 shots on goal. Defensively, the Florida Panthers are allowing 2.78 goals per game and are killing 80.6 percent of their opponent’s power plays. Jacob Markstrom has allowed 12 goals on 117 shots faced, and Akira Schmid has allowed 12 goals on 98 shots.

Ottawa Senators Betting Preview


The Ottawa Senators beat the Islanders, lost to the Flyers, and they play the Sharks next. The Senators have won 6 of their last 9 games.

The Ottawa Senators are averaging 2.44 goals per game and are scoring 12.8 percent of their power play opportunities. Tim Stutzle leads Ottawa with 5 goals, Claude Giroux has 5 assists, and Drake Batherson has 21 shots on goal. Defensively, the Ottawa Senators are allowing 2.56 goals per game and are killing 79.4 percent of their opponent’s power plays. Linus Ullmark has allowed 9 goals on 164 shots faced, and Samuel Ersson has given up 12 goals on 70 shots.

Why the Ottawa Senators will win

Why the Florida Panthers will win

Total Goals Facts

Ottawa Senators Player Prop Facts

Florida Panthers Player Prop Facts

Florida Panthers vs Ottawa Senators Injury Report


The Senators will be without William Eklund, Thomas Chabot, and Kurtis MacDermid.

The Panthers will be without Jacob Markstrom, Jonah Gadjovich, Aleksander Barkov, and Brad Marchand.

Florida Panthers vs Ottawa Senators Prediction


I believe the Panthers are the better team, and they’re putting together an offensive clinic all of a sudden. However, the Panthers continue to watch their injury list get longer by the week as they’re now down their starting goalie. The Senators have played well in their own right and have been at their best at home. This is also a revenge spot for the Senators with Brady Tkachuk returning to Ottawa. Expect a hostile crowd and chippiness on the ice. Throw me some plus money, and I’d side with the Panthers. Give me a pick em price, and given the Panthers injuries, I’ll lean Senators at home.

Randy Chambers's Pick: Ottawa Senators

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