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Detroit Red Wings vs St. Louis Blues Prediction 10/28/2025 Today’s NHL Picks

Oct 17, 2025; Detroit, Michigan, USA; Detroit Red Wings center Dylan Larkin (71) scores the game winning goal in overtime against Tampa Bay Lightning goaltender Andrei Vasilevskiy (88) at Little Caesars Arena. Mandatory Credit: Brian Bradshaw Sevald-Imagn Images

Oct 17, 2025; Detroit, Michigan, USA; Detroit Red Wings center Dylan Larkin (71) scores the game winning goal in overtime against Tampa Bay Lightning goaltender Andrei Vasilevskiy (88) at Little Caesars Arena. Mandatory Credit: Brian Bradshaw Sevald-Imagn Images

MATCHUP Detroit Red Wings St. Louis Blues
Team Records 7-3-0 3-6-1
Where Enterprise Center, St. Louis, MO
When Tuesday, October 28, 2025
Time 08:15 PM EDT
TV ESPN+

The Detroit Red Wings and the St. Louis Blues meet Tuesday in NHL action from the Enterprise Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Detroit Red Wings vs. St. Louis Blues prediction.

Detroit Red Wings Recap

The Detroit Red Wings come into this game looking to build on their 6-4 win over St. Louis last time out to sit at 6-3 this season. After this game, Detroit will head on the road again for a game against the Los Angeles Kings.

Red Wings Snap Two-Game Losing Skid

Dylan Larkin leads Detroit with 13 points including 6 goals and 7 assists while Alex DeBrincat has 8 points with 7 assists and Emmitt Finnie has 8 points with 4 goals and 4 assists. Lucas Raymond has 6 points with 4 assists while J.T. Compher and Patrick Kane each have 5 points with 2 goals and 3 assists apiece. Mason Appleton’s added 4 points with 3 goals and Andrew Copp has 4 points with 3 assists while Jonatan Berggren has 4 points with 2 goals and 2 assists. Simon Edvinsson has 3 goals as well on the year. Cam Talbot has gone 3-1 with a 2.98 GAA and an .870 save percentage while John Gibson is 3-2 with a 3.46 GAA and an .890 save percentage so far this season in goal for Detroit.

St. Louis Blues Recap

The St. Louis Blues come into this game looking to bounce back from their 6-3 loss at the hands of the Pittsburgh Penguins last time out to sit at 3-5-1 this season. After this game, the Blues will take on the Vancouver Canucks at home.

Blues Drop 4th Straight

Entering Monday, Jake Neighbours leads the Blues with 7 points including a team-high 6 goals while Robert Thomas has 6 points with 5 assists and Jimmy Snuggerud has 6 points with 3 goals and 3 assists and Jordan Kyrou and Pavel Buchnevich each have 6 points with 2 goals and 4 assists. Colton Parayko has 4 assists while Pius Suter has 4 points with 3 goals and Justin Faulk has 4 points with 3 assists. Nathan Walker, Dylan Holloway, Tyler Tucker and Brayden Schenn each have 3 points with a goal and 2 assists. Jordan Binnington has gone 2-3-1 with a 3.12 GAA and an .872 save percentage in goal for St. Louis while Joel Hofer is 1-1 with a 6.23 GAA and a .789 save percentage so far this season. 

Detroit Red Wings @ St. Louis Blues Betting Trends: October 28, 2025

Why the St. Louis Blues will win

Why the Detroit Red Wings will win

Total Goals Facts

St. Louis Blues Player Prop Facts

Detroit Red Wings Player Prop Facts

Matchup/League Facts

Detroit Red Wings vs. St. Louis Blues Prediction

I’m on the Red Wings here. I just don’t like what I’m seeing from St. Louis up to this point coming into this game as they’ve been struggling with consistency and have now allowed 6+ goals in 3 straight games. The Red Wings have been solid for the better part of the year and I think that the Red Wings get the job done once again in this game. Give me Detroit here.

Chris Ruffolo's Pick: Detroit -115

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