Chicago Blackhawks vs St. Louis Blues Prediction 3/22/25 NHL Picks

The Chicago Blackhawks and the St. Louis Blues meet Saturday in NHL action from the Enterprise Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago Blackhawks vs. St. Louis Blues prediction.

Matchup History

The St. Louis Blues won both meetings between these two teams this season, starting with a 6-2 win in Chicago back on December 31st, 2024 and then a 6-5 shootout win in St. Louis on February 8th, 2025. The wins made it 8 wins for the Blues in the last 10 head-to-head matchups between these two teams.

Chicago Blackhawks Recap

The Chicago Blackhawks come into this game looking to bounce back from a 3-1 loss at the hands of the Los Angeles Kings last time out to fall to 20-40-9 on the year. After this game, Chicago will head back home for a matchup with the Philadelphia Flyers.

Blackhawks Drop Sixth In A Row

Connor Bedard has a team-high 54 points with 19 goals and a team-high 35 assists while Ryan Donato has 51 points with 23 goals. Teuvo Teravainen has 53 points with 15 goals and 38 assists. Tyler Bertuzzi also has 37 points with 18 goals and 19 assists and Nick Foligno’s added 27 points with 12 goals and 15 assists so far this season. In goal, Arvid Soderblom is 8-16-7 with a 3.14 GAA and a .901 save percentage while Spencer Knight is 2-4 with a 2.84 GAA and a .909 save percentage as well in his time with the Blackhawks.

Why the Chicago Blackhawks will win

• The Blues have lost each of their last four day games at Enterprise Center following a home win.
• The Blackhawks have won three of their last four games at Enterprise Center against opponents on a winning streak.
• The Blues have failed to cover the puck line in each of their last nine day games at Enterprise Center following a home win.
• The Blackhawks have covered the puck line in each of their last six games at Enterprise Center against opponents on a winning streak.

Chicago Blackhawks Player Prop Facts

• Tyler Bertuzzi has scored at least one goal in three of the Blackhawks’ last four day games.
• Ryan Donato has recorded at least one assist in six of the Blackhawks’ last seven games as road underdogs against Western Conference opponents.
• Ryan Donato has recorded at least one point in eight of his last nine appearances against the Blues.
• Teuvo Teravainen ranks T1st in the league for shootout goals (3) this season.

St. Louis Blues Recap

The St. Louis Blues come into this game looking to add on to their 4-3 OT win over the Vancouver Canucks last time out to improve to 35-28-7 on the year. After this game, St. Louis will welcome the Nashville Predators to town.

Blues Win 4th Straight

Jordan Kyrou leads the Blues in scoring with 59 points including a team-high 29 goals and 30 assists while Robert Thomas has 56 points with 17 goals and 39 assists this season. Dylan Holloway has 56 points with 23 goals and 33 assists while Pavel Buchnevich has 47 points with 14 goals and 33 assists. Brayden Schenn’s added 45 points with 16 goals and 29 assists and Jake Neighbours has 38 points with 19 goals and 19 assists. Joel Hofer has gone 13-7-3 with a 2.71 GAA and a .903 save percentage in goal for St. Louis so far this season while Jordan Binnington is 22-21-4 with a 2.81 GAA and an .897 save percentage.

Why the St. Louis Blues will win

• The Blackhawks have lost each of their last eight road games against Central Division opponents.
• The Blues have won nine of their last 10 home games against the Blackhawks.
• The Blues have covered the puck line in each of their last six games against opponents on a losing streak.
• The Blackhawks have failed to cover the puck line in seven of their last eight day games.

St. Louis Blues Player Prop Facts

• Robert Thomas has scored a goal in each of the Blues’ last four games as home favorites against Central Division opponents.
• Dylan Holloway has recorded at least one assist in each of the Blues’ last seven games as favorites against Western Conference opponents.
• Dylan Holloway has recorded at least one point in each of the Blues’ last 10 games as favorites.
• Zachary Bolduc ranks 1st amongst rookies for Plus/Minus (+14) this season.

Total Goals Facts

• Each of the Blackhawks’ last nine games against the Blues following a home loss have gone OVER the total goals line.
• Each of the Blues’ last eight day games following a win have gone OVER the total goals line.
• Four of the last five day games between two teams from the Central Division have gone OVER the total goals line.

Chicago Blackhawks vs. St. Louis Blues Prediction

I’m on the Blues here. The Blackhawks were competitive in their last trip to St. Louis, but right now, the Blackhawks are in turmoil with six straight losses and 2 goals or less scored in all six. St. Louis is just rolling right now and are not a team I’m really interested in stepping in front of if we’re being honest. The Blues have owned this matchup in the past and I don’t see the Blackhawks changing that streak in this game. Give me St. Louis in this one.