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Buffalo Sabres vs St. Louis Blues Prediction 12/29/2025 Today’s NHL Picks

Nov 6, 2025; Buffalo, New York, USA;  Buffalo Sabres right wing Alex Tuch (89) tries to screen St. Louis Blues goaltender Joel Hofer (30) as he looks to make a save during the second period at KeyBank Center. Mandatory Credit: Timothy T. Ludwig-Imagn Images

Nov 6, 2025; Buffalo, New York, USA; Buffalo Sabres right wing Alex Tuch (89) tries to screen St. Louis Blues goaltender Joel Hofer (30) as he looks to make a save during the second period at KeyBank Center. Mandatory Credit: Timothy T. Ludwig-Imagn Images

MATCHUP Buffalo Sabres St. Louis Blues
Team Records 20-14-4 15-17-8
Where Enterprise Center, St. Louis, MO
When Monday, December 29, 2025
Time 08:00 PM EST
TV ESPN+

In this article, we will formulate a Sabres vs Blues Prediction for this NHL game on Monday, December 29th. Let’s take a look at the prediction for this NHL matchup.

St. Louis Blues Preview

The Blues have 38 points this season with a 15-16-8 record, and are 18-21 ATS and 18-21 in over/under. They have an 8-8-5 home record and a 7-8-3 road record and are sitting 5th in the Central Division. They are coming off a 3-2 home win over the Predators, and their previous three games were a 1-4 road loss against the Lightning, a 6-2 road win against the Panthers, and a 2-1 home overtime loss against the Rangers.

Offensively, the Blues are averaging 2.51 goals per game and are scoring 18.6% of their power play opportunities. Defensively, they are allowing 3.36 goals per game and are killing 76.8% of their opponent’s power plays.

Robert Thomas leads the Blues with 29 points and 9 goals, while Justin Faulk also leads the team in assists with 20. Joel Hofer is the starting goalie for the Blues, and he has an 8-7-2 record, with 2.86 GAA and .900 SV%. Jordan Binnington is the backup goalie and he has a 7-9-6 record, with 3.44 GAA and .870 SV%.

Buffalo Sabres Preview

The Sabres have 42 points this season with a 19-14-4 record, and are 18-19 ATS and 16-19 in over/under. They have a 12-5-2 home record and a 7-9-2 road record and are sitting 5th in the Atlantic Division. They are coming off a 4-1 home win over the Bruins, and their previous three games were a 3-2 road overtime win against the Senators, a 3-1 road win against the Devils, and a 3-2 home shootout win against the Islanders.

Offensively, the Sabres are averaging 3.05 goals per game and are scoring 19.6% of their power play opportunities. Defensively, they are allowing 3.19 goals per game and are killing 84.6% of their opponent’s power plays.

Tage Thompson leads the Sabres with 34 points and 18 goals, while Rasmus Dahlin leads the team in assists with 24. Alex Lyon is the starting goalie for the Sabres, and he has a 9-6-3 record, with 2.87 GAA and .907 SV%. Ukko-Pekka Luukkonen is the backup goalie and he has a 6-5-1 record, with 2.58 GAA and .897 SV%.

Buffalo Sabres @ St. Louis Blues Betting Trends: December 29, 2025

Why the St. Louis Blues will win

Why the Buffalo Sabres will win

Total Goals Facts

St. Louis Blues Player Prop Facts

Buffalo Sabres Player Prop Facts

Matchup/League Facts

Sabres vs Blues Prediction

In their previous meeting earlier this season, the Blues won 3-0 on the road but both teams are tied 4-4 in their last 8 meetings. Over is 8-2 in their last 10 meetings.

In this Sabres vs Blues Prediction, the Sabres are coming as -108 road favorites. The Sabres have been the better team this season, with more points and more overall wins than the Blues, but have been significantly weaker on the road. They are one of the hottest teams in hockey lately with 8 consecutive wins, five of them on the road and are facing a Blues team that is 4-5 in their last 9 games. The Sabres have both a better offense and defense than the Blues throughout the season and also a better power play and penalty kill, so I expect them to get the job done today on the road. Take the Sabres on the moneyline.

Nikos Lagouretos's Pick: Buffalo Sabres ML

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