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Tampa Bay Buccaneers vs Los Angeles Rams Prediction 11/23/2025 Today’s NFL Picks

Nov 16, 2025; Orchard Park, New York, USA;  Tampa Bay Buccaneers quarterback Baker Mayfield (6) throws a pass against the Buffalo Bills during the second half of the game at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

Nov 16, 2025; Orchard Park, New York, USA; Tampa Bay Buccaneers quarterback Baker Mayfield (6) throws a pass against the Buffalo Bills during the second half of the game at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images

MATCHUP Tampa Bay Buccaneers Los Angeles Rams
Team Records 6-4 8-2
Spread +6.5 -105 -6.5 -115
Moneyline +250 -310
Total Over 49.5 (-112) Under 49.5 (-108)
Where SoFi Stadium, Inglewood, CA
When Sunday, November 23, 2025
Time 08:20 PM EST
TV NBC
The Tampa Bay Buccaneers and the Los Angeles Rams meet in week 12 NFL action from SoFi Stadium on Sunday night. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Tampa Bay Buccaneers vs. Los Angeles Rams prediction.

Tampa Bay Buccaneers Recap

The Tampa Bay Buccaneers come into this game looking to rebound from a 44-32 loss at the hands of the Buffalo Bills in their last game to sit at 6-4 on the year. After this game, Tampa Bay will head home to begin a homestand with a game against the Arizona Cardinals.

Buccaneers Drop Back-To-Back Games

Baker Mayfield has thrown for 2,365 yards, 17 touchdowns and 3 interceptions on 63.5% passing while  Rachaad White has a team-high 376 rushing yards and 4 touchdowns. Emeka Egbuka has a team-high 45 catches for 717 yards and 6 touchdowns while Sterling Shepard has 34 grabs for 349 yards and Cade Otton has 381 receiving yards this season. On defense, Tykee Smith has a team-high 79 total tackles and Yaya Diaby has a team-high 4 sacks. As a unit, Tampa Bay’s defense has combined for 26 sacks and 10 interceptions this season.

Los Angeles Rams Recap

The Los Angeles Rams come into this game looking to build on their 21-19 win over Seattle last time out to sit at 8-2 this season. After this game, Los Angeles will head on the road for a game against the Carolina Panthers.

Rams Win 5th In A Row

Matthew Stafford has thrown for 2,557 yards, 27 touchdowns and 2 interceptions on 66% passing while Kyren Williams has rushed for 750 yards and 6 touchdowns to lead the Rams on the ground and Blake Corum has 317 rushing yards. Puka Nacua has a team-high 73 catches for 850 yards while Davante Adams has 43 grabs for 569 yards and 10 touchdowns. Seven more Rams have 100+ receiving yards as well this season. On defense, Nate Landman has a team-high 90 total tackles including 44 solo tackles. Byron Young has a team-high 9 sacks while the Rams’ defense as a whole has combined for 27 sacks and 10 interceptions so far this season.

Tampa Bay Buccaneers @ Los Angeles Rams Betting Trends: Week 12


Why the Los Angeles Rams will win

Why the Tampa Bay Buccaneers will win

Total Points Facts

Los Angeles Rams Player Prop Facts

Tampa Bay Buccaneers Player Prop Facts

Matchup/League Facts

Tampa Bay Buccaneers vs. Los Angeles Rams Prediction

I’m on the over here. I think these are two teams with solid defenses, but not enough love goes to how efficient both offenses are. I think this is going to be a 30-24 kind of game with how Tampa Bay continues to be competitive as an underdog, and the Rams still have a balanced attack with Williams, Stafford and Nacua all clicking right now. Give me the over.

Chris Ruffolo's Pick: Over 49.5

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