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Rams vs Cardinals Prediction 12/7/2025 Today’s NFL Picks

Nov 30, 2025; Charlotte, North Carolina, USA; Los Angeles Rams tight end Colby Parkinson (84) celebrates with Los Angeles Rams quarterback Matthew Stafford (9) during the fourth quarter against the Carolina Panthers at Bank of America Stadium. Mandatory Credit: Scott Kinser-Imagn Images

Nov 30, 2025; Charlotte, North Carolina, USA; Los Angeles Rams tight end Colby Parkinson (84) celebrates with Los Angeles Rams quarterback Matthew Stafford (9) during the fourth quarter against the Carolina Panthers at Bank of America Stadium. Mandatory Credit: Scott Kinser-Imagn Images

MATCHUP Los Angeles Rams Arizona Cardinals
Team Records 9-3 3-9
Spread -8.5 -105 +8.5 -115
Moneyline -455 +350
Total Over 47.5 (-110) Under 47.5 (-110)
Where State Farm Stadium, Glendale, AZ
When Sunday, December 7, 2025
Time 04:25 PM EST
TV FOX
In this article we will formulate a Rams vs Cardinals prediction for this NFL game on Sunday, December 7th at State Farm Stadium in Glendale, Arizona. Let’s take a look at the prediction for this week 14 matchup.

Los Angeles Rams Betting Preview

The Los Angeles Rams are 9-3 this season after they lost to Carolina by a score of 31-28 in their last game. Los Angeles led 21-17 at halftime and 28-24 in the fourth quarter, but they allowed a touchdown with about six minutes left for the loss. The Rams out gained Carolina by a total of 379-358, went 2-5 on third downs, and lost the turnover battle by a total of 3-0 in the game. Matthew Stafford went 18-28 for 243 yards, two touchdowns, and two interceptions, while Blake Corum rushed seven times for 81 yards and one score. Xavier Smith led the receivers with three catches for 82 yards in the loss. 

Prior to that game, Los Angeles defeated the Buccaneers by a score of 34-7 and the Seahawks by a score of 21-19. The Rams have won six of their last seven games and they are currently tied for first in the NFC West standings. Los Angeles has scored 27.8 points per game with 246.6 passing yards and 113.5 rushing yards per game, while they have allowed 17.5 points against per game this season. Matthew Stafford has thrown for 3,073 yards, 32 touchdowns, and four interceptions, while Puka Nacua has caught 86 passes for 1,019 yards and four scores this season. 

Arizona Cardinals Betting Preview

The Arizona Cardinals are 3-9 this year after they lost to Tampa Bay by a score of 20-17 in their last game. Arizona only managed three points in the first two quarters and trailed 10-3 at halftime, but they did score 14 points in the second half in the close loss. The Cardinals out gained TB by a total of 386-279, went 3-8 on third downs, and lost the turnover battle by a total of 2-0 in the game. Jacoby Brissett went 29-40 for 301 yards, two touchdowns, and one interception, while Bam Knight rushed 11 times for 62 yards. Trey McBride led the receivers with eight receptions for 82 yards and one score in the loss. 

Prior to that game, Arizona lost to the Jaguars by a score of 27-24 and the 49ers by a score of 41-22. The Cardinals have lost four games in a row and they are currently last in the NFC West standings. Arizona has scored 22.1 points per game with 236.7 passing yards and 100.6 rushing yards per game, while they have allowed 25.3 points against per game this season. Jacoby Brissett has thrown for 2,188 yards, 13 touchdowns, and four interceptions, while Trey McBride has 88 receptions for 879 yards and eight scores this year. 

Why the Los Angeles Rams will win

Total Points Facts

Arizona Cardinals Player Prop Facts

Los Angeles Rams Player Prop Facts

Matchup/League Facts

Rams vs Cardinals Prediction 

Arizona comes into this contest on a four game losing streak and they have allowed at least 27 points in three of those four losses. The Cardinals have a decent offensive attack, but their defense has been pretty rough all season. Los Angeles has been one of the best teams in the NFL this year, but they dropped an ugly game last week at Carolina. The Rams have scored at least 28 points in four of their last five and I think they are going to have a huge day offensively here. Take LA to cover on the road.

David Racey is 79-58 (58%) in the NFL this season and he is currently #2 on the NFL Leaderboard. Click here for his premium plays for this week!

David Racey's Pick: Rams -7.5

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