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New York Giants vs New Orleans Saints Prediction 10/5/2025 Today’s NFL Picks

Sep 28, 2025; East Rutherford, New Jersey, USA; New York Giants quarterback Jaxson Dart (6) runs with the ball against the Los Angeles Chargers during the fourth quarter at MetLife Stadium. Mandatory Credit: Brad Penner-Imagn Images

Sep 28, 2025; East Rutherford, New Jersey, USA; New York Giants quarterback Jaxson Dart (6) runs with the ball against the Los Angeles Chargers during the fourth quarter at MetLife Stadium. Mandatory Credit: Brad Penner-Imagn Images

MATCHUP New York Giants New Orleans Saints
Team Records 1-4 1-4
Where Caesars Superdome, New Orleans, LA
When Sunday, October 5, 2025
Time 01:00 PM EDT
TV CBS

The New York Giants and the New Orleans Saints meet in week 5 NFL action from Caesars Superdome on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Giants vs. New Orleans Saints prediction.

New York Giants Recap

The New York Giants come into this game looking to build on their 21-18 win over the Los Angeles Chargers last time out to sit at 1-3 this season. After this game, the Giants will head home for a game against the Philadelphia Eagles.

Giants Pick Up First W Of Season

Jaxson Dart has thrown for 111 yards and a touchdown on 65% passing. Cam Skattebo also has 181 rushing yards with 2 touchdowns while Malik Nabers leads the Giants with 18 catches for 271 yards and 2 touchdowns but will miss the rest of the season because of injury and Wan’Dale Robinson has 18 grabs for 237 yards and a TD. Darius Slayton also has 135 receiving yards as well this season. On defense, Bobby Okereke has a team-high 38 total tackles including 18 solo tackles while Paulson Adebo has 31 total tackles including a team-high 26 solo tackles. Brian Burns also leads the Giants with 5 sacks as well this season. As a unit, the Giants have combined for 10 sacks and 3 interceptions so far this season.

New Orleans Saints Recap

The New Orleans Saints come into this game looking to come back from a 31-19 loss at the hands of the Buffalo Bills last time out to fall to 0-4 on the year. After this game, the Saints will take on the New England Patriots at home.

Saints Still Searching For First W

Spencer Rattler has thrown for 765 yards, 5 touchdowns and an interception on 67.1% passing while Alvin Kamara has 256 rushing yards and a touchdown to lead the Saints on the ground. Juwan Johnson has a team-high 204 receiving yards with a touchdown on 22 receptions while Chris Olave has a team-high 26 catches for 185 yards and Rashid Shaheed’s added 174 receiving yards and a TD as well. On defense, Demario Davis has a team-high 38 total tackles while Carl Granderson leads New Orleans with 4.5 sacks. As a unit, the Saints have combined for 11 sacks and an interception so far this season.

New York Giants @ New Orleans Saints Betting Trends: Week 5

Why the New Orleans Saints will win

Why the New York Giants will win

Total Points Facts

New Orleans Saints Player Prop Facts

New York Giants Player Prop Facts

Matchup/League Facts

New York Giants vs. New Orleans Saints Prediction

I’m on the Giants and the points in this one. I get the case to be made for the Saints laying points at home and New Orleans has been surprisingly competitive so far this season. However, I still think that the Giants were more impressive with their win over the Chargers last week, and I shudder to think of what could happen here for Spencer Rattler against this Giants pass rush. I think that the Giants get a solid win on the road here so give me New York and the points to be safe.

Chris Ruffolo's Pick: New York Giants +1.5

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