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Los Angeles Rams vs Jacksonville Jaguars Prediction 10/19/2025 Today’s NFL Picks

Sep 28, 2025; Inglewood, California, USA; Los Angeles Rams running back Kyren Williams (23) and wide receiver Puka Nacua (12) flex as they get ready for the game against the Indianapolis Colts at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

Sep 28, 2025; Inglewood, California, USA; Los Angeles Rams running back Kyren Williams (23) and wide receiver Puka Nacua (12) flex as they get ready for the game against the Indianapolis Colts at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

MATCHUP Los Angeles Rams Jacksonville Jaguars
Team Records 5-2 4-3
Where Wembley Stadium, London
When Sunday, October 19, 2025
Time 09:30 AM EDT
TV NFL Net
The Los Angeles Rams and Jacksonville Jaguars meet Sunday in NFL action at Wembley Stadium. Here’s a Los Angeles Rams vs Jacksonville Jaguars Prediction. This article will include a Los Angeles Rams vs Jacksonville Jaguars Pick.

Los Angeles Rams Betting Preview


The Los Angeles Rams beat the Ravens, lost to the 49ers, and they play the Ravens next. The Rams have won 10 of their last 14 regular season games. Matthew Stafford is completing 66.5 percent of his passes for 1,684 yards, 12 touchdowns, and 2 interceptions. Puka Nacua and Davante Adams have combined for 1,015 receiving yards and 5 touchdowns, while Tutu Atwell has 4 receptions.

The Los Angeles Rams ground game is averaging 105.8 yards per contest, and Kyren Williams leads the way with 418 yards and 2 touchdowns. Defensively, Los Angeles is allowing 18.3 points and 306.8 yards per game. Nate Landman leads the Los Angeles Rams with 58 tackles, Byron Young has 7.5 sacks and Kam Curl has 2 interceptions.

Jacksonville Jaguars Betting Preview


The Jacksonville Jaguars beat the Chiefs, lost to the Seahawks, and they play the Raiders next. The Jacksonville Jaguars have won 5 of their last 8 games. Trevor Lawrence is completing 61.1 percent of his passes for 1,324 yards, 8 touchdowns, and 5 interceptions. Brenton Strange and Brian Thomas Jr. have combined for 538 receiving yards and 1 touchdown, while Travis Hunter has 20 receptions.

The Jacksonville Jaguars ground game is averaging 124 yards per contest, and Travis Etienne Jr. leads the way with 470 yards and 2 touchdowns. Defensively, Jacksonville is allowing 20 points and 347.8 yards per game. Foyesade Oluokun leads the Jacksonville Jaguars with 53 tackles, Arik Armstead has 3.5 sacks and Devin Lloyd has 4 interceptions.

Why the Jacksonville Jaguars will win

Why the Los Angeles Rams will win

Total Points Facts

Jacksonville Jaguars Player Prop Facts

Los Angeles Rams Player Prop Facts

Matchup/League Facts

Los Angeles Rams vs Jacksonville Jaguars Prediction


The Jaguars have surprised up to this point, but right when you’re ready to believe in them, they have a subpar showing that reminds you of what they’ve been for the last decade. Also, even without Puka Nacua, the Rams are a talented offensive team with above-average weapons, and the Jaguars are 30th in pass defense. As I’ve said before, I’m a big fan of Sean McVay and whenever I can get the Rams at a reasonable line, I’m usually going to take it. The Rams are 11-4 ATS in their last 15 games when favorites of 3 or fewer points. The Jaguars still have some showing and proving to do. I’ll lay the small number with the Rams.

Randy Chambers's Pick: Los Angeles Rams -2.5

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