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Los Angeles Chargers vs Dallas Cowboys Prediction 12/21/2025 Today’s NFL Picks

Dec 14, 2025; Arlington, Texas, USA; Dallas Cowboys wide receiver George Pickens (3) warms up before a game against the Minnesota Vikings at AT&T Stadium. Mandatory Credit: Kevin Jairaj-Imagn Images

Dec 14, 2025; Arlington, Texas, USA; Dallas Cowboys wide receiver George Pickens (3) warms up before a game against the Minnesota Vikings at AT&T Stadium. Mandatory Credit: Kevin Jairaj-Imagn Images

MATCHUP Los Angeles Chargers Dallas Cowboys
Team Records 10-4 6-7-1
Spread +1.5 -105 -1.5 -115
Moneyline +110 -130
Total Over 49.5 (-108) Under 49.5 (-112)
Where AT&T Stadium, Arlington, TX
When Sunday, December 21, 2025
Time 01:00 PM EST
TV FOX
The Los Angeles Chargers and Dallas Cowboys meet Sunday in NFL action at AT&T Stadium. Here’s a Los Angeles Chargers vs Dallas Cowboys Prediction. This article will include a Los Angeles Chargers vs Dallas Cowboys Pick.

Los Angeles Chargers Betting Preview


The Los Angeles Chargers beat the Chiefs and Eagles, and they play the Texans next. The Los Angeles Chargers have won 6 of their last 7 games. Justin Herbert is completing 65.6 percent of his passes for 3,191 yards, 23 touchdowns, and 12 interceptions. Ladd McConkey and Keenan Allen have combined for 1,395 receiving yards and 9 touchdowns, while Oronde Gadsden II has 43 receptions.

The Los Angeles Chargers ground game is averaging 123.4 yards per contest, and Kimani Vidal leads the way with 620 yards and 3 touchdowns. Defensively, Los Angeles is allowing 20.3 points and 279.1 yards per game. Daiyan Henley leads the Los Angeles Chargers with 86 tackles, Tuli Tuipulotu has 12 sacks and Tony Jefferson has 4 interceptions.

Dallas Cowboys Betting Preview


The Dallas Cowboys lost to the Lions and Vikings, and they play the Commanders next. The Dallas Cowboys have lost 2 straight games. Dak Prescott is completing 68.4 percent of his passes for 3,931 yards, 26 touchdowns, and 10 interceptions. George Pickens and CeeDee Lamb have combined for 2,188 receiving yards and 11 touchdowns, while Jake Ferguson has 77 receptions.

The Dallas Cowboys ground game is averaging 120.8 yards per contest, and Javonte Williams leads the way with 1,113 yards and 10 touchdowns. Defensively, Dallas is allowing 30 points and 374.9 yards per game. Kenneth Murray Jr. leads the Dallas Cowboys with 74 tackles, James Houston has 5.5 sacks and Donovan Wilson has 2 interceptions.

Why the Dallas Cowboys will win

Why the Los Angeles Chargers will win

Total Points Facts

Dallas Cowboys Player Prop Facts

Los Angeles Chargers Player Prop Facts

Matchup/League Facts

Los Angeles Chargers vs Dallas Cowboys Prediction


Right when it looked like the Cowboys were turning the corner, the defense goes back to being trash, and now they’re all but out of the playoff race. The Cowboys are 29th in total defense and 31st in scoring defense. The Chargers are getting healthier on offense, and the defense is one of the more underrated units in the NFL. The Chargers are second in total defense and ninth in scoring defense. The Chargers are a good football team that can enter Super Bowl contender status if the offensive line eventually gets right.

I have zero idea why the Cowboys are favorites in this game. It makes zero sense. The Cowboys are 4-8 ATS in their last 12 games as a favorite. The Chargers are 3-0 SU this season as an underdog. This line is Looney Tunes stuff. Give me the Chargers ML.

Randy Chambers's Pick: Los Angeles Chargers ML

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