Kansas City (0-0) vs Los Angeles (0-0)
September 5, 2025 at 08:00 PM EDT
The Line: Betting Odds: Los Angeles +3 — Over/Under: +45.5
The Los Angeles Chargers and Kansas City Chiefs meet Friday in NFL action at Corinthians Arena. Here’s a Kansas City Chiefs vs Los Angeles Chargers Prediction. This article will include a Kansas City Chiefs vs Los Angeles Chargers Pick.
Los Angeles Chargers Betting Preview
The Chargers won 11 games in Jim Harbaugh’s first season and have to believe they’re a contender in the AFC this year. It was the most games the Chargers have won since the 2018 season.
Justin Herbert is only 27 years old and already has 21,000 career passing yards and 137 touchdowns. He has help in the backfield with the additions of Najee Harris and first round pick Omarion Hampton. Ladd McConkey is coming off a great rookie season, and Tre Harris adds depth at the receiver position. The offensive line got better by bringing in Super Bowl champion Mekhi Becton.
Defensively, Khalil Mack is back for another season and Daiyan Henley is a promising young linebacker. The concerns are the Chargers leave a lot to be desired on the defensive line and outside of Derwin James, the secondary can be beat. Still, the Chargers are explosive offensively and have one of the best coaches in the league. The Chargers should push for back-to-back playoff trips for the first time since the 2009 season.
Kansas City Chiefs Betting Preview
The Kansas City Chiefs have made the Super Bowl in three straight seasons and are a favorite to make it yet again. The Chiefs haven’t missed the playoffs since the 2014 season.
The Chiefs are in great hands as long as Patrick Mahomes remains upright and coach Andy Reid is on the sidelines. It’s arguably the best QB-Coach duo in NFL history. There’s offensive line issues with the Chiefs and there’s some uncertainty around receiver Rashee Rice, but you feel good when Mahomes is on the field regardless of what the rest of the roster looks like.
Defensively, the Chiefs say goodbye to Justin Reid, but this is still one of the better defenses under Steve Spagnuolo. The Chiefs have arguably the best linebacker group in Nick Bolton, Drue Tranquill, and Leo Chenal. Chris Jones is also one of the best pass rushers in the league, with 80.5 sacks and 37 pass deflections for his career.
The Chiefs aren’t perfect, mainly due to OL concerns, but the key guys have shown they will find a way to win when the lights get brightest.
Kansas City Chiefs vs Los Angeles Chargers Prediction
These foreign games are strange to cap as you have to factor in field conditions as well as travel and acclimatization. A lot of these fields in other countries have poor traction and can play a role in player movement. With that said, the Chargers have played the Chiefs tough in recent years, and you can argue they’re just as talented. While the Chiefs keep finding ways to make the Super Bowl, they’ve been pedestrian throughout the regular season, especially last year.
The Chiefs have offensive line issues and are more limited offensively overall compared to past years. The Rice suspension doesn’t help. The underdog has covered in five of the last eight games between the Chiefs and Chargers. Despite the Chiefs winning the last seven games against the Chargers, those games were decided by an average of 5.14 points. I’ll grab the free field goal with the Chargers.