Indianapolis Colts vs Jacksonville Jaguars Prediction 12/7/2025 Today’s NFL Picks

Nikos Lagouretos

14 hours ago

Jan 5, 2025; Indianapolis, Indiana, USA; A pass intended for Indianapolis Colts wide receiver Michael Pittman Jr. (11) falls incomplete during a game against the Jacksonville Jaguars at Lucas Oil Stadium. Mandatory Credit: Christine Tannous/USA TODAY Network via Imagn Images

MATCHUP	Indianapolis Colts	Jacksonville Jaguars
Team Records	8-4	8-4
Spread	-1.5 -112	+1.5 -108
Moneyline	-125	+105
Total	Over 47.5 (-115)	Under 47.5 (-105)
Where	EverBank Stadium, Jacksonville, FL
When	Sunday, December 7, 2025
Time	01:00 PM EST
TV	CBS

In this article, we will formulate a Colts vs Jaguars Prediction for this NFL Week 13 game on Sunday, December 7th. Let’s take a look at the prediction for this NFL matchup.

Jacksonville Jaguars Preview

The Jacksonville Jaguars have an 8-4 record this season and are sitting first in the AFC South. They are 7-4-1 ATS, 6-6 in Over/Under and have a 4-2 home record and a 4-2 away record. The Jaguars are coming off a 25-3 away win against the Tennessee Titans and will face the Jets, Broncos and Colts next.

Offensively, the Jaguars average 24.3 points per game, ranking 11th in the NFL, while defensively, they allow 21.1 points per game, which is 12th. Jacksonville averages 326 total yards per game (202.8 passing and 123.3 rushing), while allowing 312.5 total yards per game (82.4 rushing and 230.1 passing).

Trevor Lawrence leads the Jaguars with 2636 passing yards with 59.7% completed passes and 16 touchdowns. Travis Etienne leads the team in rushing yards with 843, while Parker Washington has a team-high 36 receptions for 447 receiving yards, and three touchdowns. Defensively, Foyesade Oluokun has a team-high 96 total tackles (48 of them solo), while Josh Hines-Allen leads the team in sacks, with 6.

Indianapolis Colts Preview

The Indianapolis Colts have an 8-4 record this season and are sitting first in the AFC South. They are 7-4-1 ATS, 6-6 in Over/Under and have a 6-1 home record and a 2-3 away record. The Colts are coming off a 16-20 home loss against the Houston Texans and will face the Seahawks, 49ers and Jaguars next.

Offensively, the Colts average 29.8 points per game, ranking 1st in the NFL, while defensively, they allow 20.8 points per game, which is 9th. Indianapolis averages 375.4 total yards per game (241 passing and 134.4 rushing), while allowing 344.5 total yards per game (98.3 rushing and 246.3 passing).

Daniel Jones leads the Colts with 3041 passing yards with 67.9% completed passes and 19 touchdowns. Jonathan Taylor leads the team in rushing yards with 1282, while Michael Pittman Jr. has a team-high 60 receptions for 620 receiving yards, and seven touchdowns. Defensively, Zaire Franklin has a team-high 87 total tackles (43 of them solo), while Laiatu Latu leads the team in sacks, with 5.5.

Indianapolis Colts @ Jacksonville Jaguars Betting Trends: Week 14

Why the Jacksonville Jaguars will win

The Colts have lost each of their last nine games at EverBank Stadium.
The Jaguars have won each of their last five games as home underdogs against the Colts.
The Colts have failed to cover the spread in each of their last six games as road favorites following a Division game.
The Jaguars have covered the spread in seven of their last eight games as underdogs against the Colts.
The Jaguars have won the first quarter in three of their last four games as underdogs.
The Jaguars have scored the first touchdown in each of their last six Sunday games at EverBank Stadium.
The Colts have lost the first half in four of their last five games as slight favorites (<-3.5 points).

Why the Indianapolis Colts will win

The Colts have won each of their last five December games against AFC South opponents.
The Jaguars have lost each of their four previous games without Josh Hines-Allen.
The Jaguars have failed to cover the spread in seven of their eight previous games without Brenton Strange.
The Colts have covered the spread in each of their last five road games against AFC South opponents.
The Jaguars have lost the first half in eight of their last nine games as home underdogs following a win.
The Colts have won the first quarter in each of their last eight road games against AFC opponents.
The Colts have scored the first touchdown in each of their last 10 games.

Total Points Facts

Each of the Colts’ last six December games as favorites have gone OVER the total points line.
Seven of the Jaguars’ last eight Sunday games at EverBank Stadium have gone UNDER the total points line.
Each of the last five Sunday games at EverBank Stadium have gone UNDER the total points line.

Jacksonville Jaguars Player Prop Facts

Brian Thomas has scored at least one touchdown in each of the Jaguars’ last four games as underdogs against teams on a losing streak.
Trevor Lawrence has recorded 229+ passing yards in six of his last seven December appearances against AFC opponents.
Trevor Lawrence has recorded 22+ completions in four of his five previous December home appearances.
Jakobi Meyers has recorded 41+ receiving yards in each of his last 12 appearances following a win.
Trevor Lawrence has recorded 18+ rushing yards in five of the Jaguars’ last six games.
Jakobi Meyers has recorded 48+ rushing and receiving yards in each of his seven previous appearances in Florida.
Heading into Week 14, Devin Lloyd has recorded the equal-most interceptions in a single game this season (2 vs 49ers, Week 4).

Indianapolis Colts Player Prop Facts

Jonathan Taylor has scored the first touchdown in each of his last three December appearances with the Colts a road favorites against AFC opponents.
Jonathan Taylor has scored two touchdowns in four of his last five December appearances with the Colts as road favorites.
Daniel Jones has recorded 23+ completions in three of the Colts’ last four Sunday road games.
Daniel Jones has recorded 262+ passing yards in three of the Colts’ last four road games.
Jonathan Taylor has scored at least one touchdown in each of his 10 previous December appearances with the Colts as favorites.
Josh Downs has recorded 34+ receiving yards in each of his last nine appearances against AFC South opponents.
Michael Pittman Jr. has scored the last touchdown in three of his last four appearances with the Colts as road favorites against AFC South opponents.
Daniel Jones has recorded 15+ rushing yards in each of his last 14 appearances in Sunday games played on the East Coast.
Jonathan Taylor has recorded 117+ rushing and receiving yards in each of the Colts’ last six games against AFC South opponents.
Heading into Week 14, Jonathan Taylor ranks 1st in the NFL in rushing yards (1282) this season.

Matchup/League Facts

Jaguars – five different players have recorded 90+ receiving yards in a game this season – equal-most in the NFL, heading into Week 14.
Heading into Week 14, the Jaguars rank 1st in the NFL in rushing yards allowed per game (82.4) this season.
Heading into Week 14, the Colts rank 1st in the NFL in points per game (29.8) this season.
Heading into Week 14, the Colts rank 32nd in the NFL in total punt yards (1434) this season.

Colts vs Jaguars Prediction

In this Colts vs Jaguars Prediction, the Colts are coming as -1.5-point road favorites. Both teams have identical overall records and ATS records. The Jaguars are coming into this matchup in better form, as they are 4-1 in their last 5 games and have twice as many home wins than the Colts have on the road. On the flip side, the Colts are 1-3 in their last 4 games, including back-to-back road defeats. The Jags dominate the Colts in Jacksonville, having won their last five home meetings and I like them as home dogs in this spot. Take the Jaguars on the moneyline for plus money in this one.