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Indianapolis Colts vs Cincinnati Bengals Prediction 8/23/2025 Today’s NFL Picks

Cincinnati Bengals cornerback Josh Newton (28) attempts to tackle Indianapolis Colts running back Demetric Felton (36) in the fourth quarter of the NFL preseason game at Paycor Stadium in Cincinnati on Thursday, Aug. 22, 2024.

Cincinnati Bengals cornerback Josh Newton (28) attempts to tackle Indianapolis Colts running back Demetric Felton (36) in the fourth quarter of the NFL preseason game at Paycor Stadium in Cincinnati on Thursday, Aug. 22, 2024.

Indianapolis (0-2) vs Cincinnati (1-1)

August 23, 2025 at 01:00 PM EDT

The Line: Betting Odds: Cincinnati -2.5 — Over/Under: +35.5

(Get latest betting odds)

In this article, we will formulate a Colts vs Bengals Prediction for this NFL Week 3 Preseason game on Saturday, August 23rd at the Paycor Stadium. Let’s take a look at the prediction for this NFL matchup.

Cincinnati Bengals Preview

The Bengals have a 1-1 record in the preseason, and they average 29 points per game, while allowing 25.5 points per game. They are coming off a 31-17 road victory in Washington, where they outgained their opponents by 293-270 yards and had 49 total plays. Cincinnati had 206 passing yards, 87 rushing yards, and 26/40 completed passes, while they won the turnover battle by 0-2. The Bengals were 6-15 on third down conversions and were 3-3 in the red zone.

Jake Browning led the team with 16/25 passes and 159 passing yards, with two touchdowns, while Joe Burrow had 9/14 passes for 62 yards. Tahj Brooks had a team-high 47 rushing yards, while Mitchell Tinsley caught 5 passes for a team-high 73 receiving yards and 2 touchdowns. Defensively, Shaka Heyward and Barrett Carter led the Bengals with 7 total tackles apiece, while Barrett Carter and Tycen Anderson had one interception each.

The Bengals lost their first game of the preseason by 27-34 on the road against the Eagles. They got outgained by their opponents by 325-432 yards and had 60 total plays. The Bengals were 3-12 on third down conversions and 2-3 in the red zone.

Indianapolis Colts Preview

The Colts have a 0-2 record in the preseason, and they average 17.5 points per game, while allowing 23.5 points per game. They are coming off a 10-23 home defeat by Green Bay as they outgained their opponents by 360-356 yards and had 62 total plays. They had 267 passing yards, 93 rushing yards, and 23/41 completed passes, while winning the turnover battle by 0-1. The Colts went 3-11 on third down conversions and were 1-4 in the red zone.

Daniel Jones led Indianapolis with 7/11 passes and a team-high 101 passing yards, while Anthony Richardson Sr. had 6/11 passes with 73 yards. DJ Giddens had a team-high 28 rushing yards, while Coleman Owen caught 4 passes for a team-high 46 receiving yards. Defensively, Eric Johnson II led the Colts with 10 total tackles, 3 of them solo, while Chris Lammons had one sack.

The Colts lost their first game of the preseason by 16-24 on the road against the Ravens. They outgained their opponents by 336-226 yards and had 78 total plays. The Colts were 6-19 on third down conversions and 1-3 in the red zone.

Colts vs Bengals Prediction

In their most recent meeting back in 2023, the Bengals won 34-14 at home, covering the -2.5-point spread and the game went over the 44.5-point total. They are 3-1 in their last 4 head-to-head meetings, and have won their last four meetings in Cincinnati. They are 6-3 against the spread in their last 9 meetings, and over is 4-0 in their last 4 meetings.

In this Colts vs Bengals Prediction, the Bengals are coming as -2.5-point home favorites. The Colts have lost both preseason games so far, and they average 11.5 points less than the Bengals. The Bengals also dominate the Colts in Cincinnati, and I will not pick a struggling road favorite in a preseason game. I like the value with the home team that looks better in the preseason so far. The line has also shifted in favor of the Bengals, as they went from underdogs to favorites. Take the Cincinnati Bengals in this one.

Nikos Lagouretos's Pick: Cincinnati Bengals -2.5

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