Houston Texans vs Indianapolis Colts Prediction 11/30/2025 Today’s NFL Picks

Nikos Lagouretos

8 hours ago

Oct 27, 2024; Houston, Texas, USA; Houston Texans defensive end Danielle Hunter (55) sacks Indianapolis Colts quarterback Anthony Richardson (5) during the fourth quarter at NRG Stadium. Mandatory Credit: Troy Taormina-Imagn Images

MATCHUP	Houston Texans	Indianapolis Colts
Team Records	6-5	8-3
Spread	+4.5 -115	-4.5 -105
Moneyline	+180	-218
Total	Over 44.5 (-115)	Under 44.5 (-105)
Where	Lucas Oil Stadium, Indianapolis, IN
When	Sunday, November 30, 2025
Time	01:00 PM EST
TV	CBS

In this article, we will formulate a Texans vs Colts Prediction for this NFL Week 13 game on Sunday, November 30th. Let’s take a look at the prediction for this NFL matchup.

Indianapolis Colts Preview

The Indianapolis Colts have an 8-3 record this season and are sitting first in the AFC South. They are 7-3-1 ATS, 6-5 in Over/Under and have a 6-0 home record and a 2-3 away record. The Colts are coming off a 20-23 away loss against the Kansas City Chiefs and will face the Jaguars and Seahawks next.

Offensively, the Colts average 31 points per game, ranking 1st in the NFL, while defensively, they allow 20.8 points per game, which is 9th. Indianapolis averages 384 total yards per game (245.2 passing and 138.8 rushing), while allowing 342.7 total yards per game (97.4 rushing and 245.3 passing).

Daniel Jones leads the Colts with 2840 passing yards with 69.1% completed passes and 17 touchdowns. Jonathan Taylor leads the team in rushing yards with 1197, while Michael Pittman Jr. has a team-high 59 receptions for 607 receiving yards, and seven touchdowns. Defensively, Nick Cross has a team-high 77 total tackles (46 of them solo), while Laiatu Latu leads the team in sacks, with 6.

Houston Texans Preview

The Houston Texans have a 6-5 record this season and are sitting third in the AFC South. They are 5-6 ATS, 3-7-1 in Over/Under and have a 4-2 home record and a 2-3 away record. The Texans are coming off a 23-19 home win against the Buffalo Bills and will face the Chiefs and Cardinals next.

Offensively, the Texans average 22.1 points per game, ranking 21st in the NFL, while defensively, they allow 16.5 points per game, which is 2nd. Houston averages 323.4 total yards per game (215.7 passing and 107.6 rushing), while allowing 264.3 total yards per game (92.2 rushing and 172.1 passing).

C.J. Stroud leads the Texans with 1702 passing yards with 66.5% completed passes and 11 touchdowns. Nick Chubb leads the team in rushing yards with 435, while Nico Collins has a team-high 52 receptions for 697 receiving yards, and four touchdowns. Defensively, Azeez Al-Shaair has a team-high 71 total tackles (34 of them solo), while Danielle Hunter leads the team in sacks, with 11.

Houston Texans @ Indianapolis Colts Betting Trends: Week 13

Why the Indianapolis Colts will win

The Colts have won each of their last seven games at Lucas Oil Stadium.
The Texans have lost each of their last six road games against teams that held a winning record.
The Colts have covered the spread in seven of their last eight games against AFC South opponents.
The Texans have failed to cover the spread in each of their last five games as underdogs following a home win.
The Colts have won the first quarter in nine of their last 10 Sunday games against the Texans.
The Colts have won the first half in each of their last six Week 13 home games against AFC opponents.
The Colts have scored the first touchdown in each of their last nine games.

Why the Houston Texans will win

The Texans have won 12 of their last 13 road games against AFC South opponents.
The Colts have lost five of their last six November games at Lucas Oil Stadium.
The Texans have covered the spread in eight of their last nine games as road underdogs against AFC South opponents.
The Colts have failed to cover the spread in five of their last six November home games against AFC opponents.
The underdogs have won the first quarter in four of the last five games between the Texans and Colts.
The Texans have won the first half in six of their last seven Sunday games against teams that held a winning record.

Total Points Facts

Eight of the Texans’ last nine Week 13 games have gone UNDER the total points line.
Each of the Colts’ last four games against AFC South opponents have gone OVER the total points line.
Four of the last five games between teams from the same division have gone UNDER the total points line.

Indianapolis Colts Player Prop Facts

Jonathan Taylor has scored the first touchdown in four of the Colts’ last five November games as favorites.
Jonathan Taylor has scored two or more touchdowns in four of the Colts’ last five games as moderate favorites (-3.5 to -7.0 points).
Daniel Jones has recorded 21+ completions in four of the Colts’ last five games at Lucas Oil Stadium.
Josh Downs has recorded 34+ receiving yards in each of his last eight appearances against AFC South opponents.
Jonathan Taylor has recorded 96+ rushing yards in each of the Colts’ last six games as moderate favorites (-3.5 to -7.0 points).
Jonathan Taylor has recorded 122+ rushing and receiving yards in seven of his last eight appearances with the Colts as home favorites against AFC South opponents.
Daniel Jones has recorded 255+ passing yards in four of the Colts’ last five games.
Jonathan Taylor has scored at least one touchdown in each of his eight previous appearances against the Texans.
Jonathan Taylor has scored the last touchdown in three of the Colts’ last four November games as favorites.
Heading into Week 13, Jonathan Taylor ranks 1st in the NFL in rushing yards (1197) this season.

Houston Texans Player Prop Facts

Nick Chubb has recorded 16+ rushing yards in each of his last 93 appearances.
C.J. Stroud has recorded 247+ passing yards in six of his eight previous November appearances.
Christian Kirk has recorded 25+ rushing and receiving yards in each of his last 29 appearances with his team as an underdog.
Christian Kirk has recorded 22+ receiving yards in each of his last 29 appearances with his team as an underdog.
Joe Mixon has scored a touchdown in each of his last five appearances against the Colts.
Davis Mills has recorded 22+ completions in four of his last five appearances as a starter.
Heading into Week 13, Ka’imi Fairbairn ranks T1st in the NFL in made field goals (25) this season.

Matchup/League Facts

Colts – four different players have recorded 2.0 sacks or more in a game this season – equal-most in the NFL, heading into Week 13.
Heading into Week 13, the Colts rank 1st in the NFL in points per game (31.0) this season.
Heading into Week 13, the Texans rank 1st in the NFL in yards allowed per game (264.3) this season.
Heading into Week 13, the Texans rank 1st in the NFL in 1st downs against (175) this season.

Texans vs Colts Prediction

In this Texans vs Colts Prediction, the Colts are coming as -4.5-point home favorites. The Colts have a better overall record this season and have been undefeated at home, but they have lost two of their last three games and are facing a red-hot Texans team that has won its last three. The Colts have the best offense in the NFL and are facing the second-best defense in the Texans and both teams are coming off low-scoring games, with 42 and 43 total points. Last season they combined for 43 total points and I expect yet another low-scoring defensive battle today. Take the under 44.5 points in this one.