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Green Bay Packers vs Arizona Cardinals Prediction 10/19/2025 Today’s NFL Picks

Green Bay Packers linebacker Edgerrin Cooper (56) tackles Arizona Cardinals running back Emari Demercado (31) on Sunday, October 13, 2024 at Lambeau Field in Green Bay, Wis. The Packers defeated the Cardinals 34-13.
Wm. Glasheen USA TODAY NETWORK-Wisconsin

Green Bay Packers linebacker Edgerrin Cooper (56) tackles Arizona Cardinals running back Emari Demercado (31) on Sunday, October 13, 2024 at Lambeau Field in Green Bay, Wis. The Packers defeated the Cardinals 34-13. Wm. Glasheen USA TODAY NETWORK-Wisconsin

MATCHUP Green Bay Packers Arizona Cardinals
Team Records 4-1-1 2-5
Where State Farm Stadium, Glendale, AZ
When Sunday, October 19, 2025
Time 04:25 PM EDT
TV FOX

In this article, we will formulate a Packers vs Cardinals Prediction for this NFL Week 7 game on Sunday, October 19th at the State Farm Stadium. Let’s take a look at the prediction for this NFL matchup.

Arizona Cardinals Preview

The Arizona Cardinals have a 2-4-0 record this season and are sitting fourth in the NFC West. They are 3-3 ATS, 3-3 in Over/Under and have a 1-2 home record and a 1-2 away record. The Cardinals are coming off a 27-31 road loss against the Indianapolis Colts and will face the Packers, Cowboys and the Seahawks next.

Offensively, the Cardinals average 21.7 points per game, ranking 20th in the NFL, while defensively, they allow 21.2 points per game, which is 14th. Arizona averages 307.0 total yards per game (193.8 passing and 113.2 rushing), while allowing 348 total yards per game (102 rushing and 246 passing).

Kyler Murray leads the Cardinals with 962 passing yards with 68.3% completed passes and 6 touchdowns. Kyler Murray leads the team in rushing yards with 173, while Trey McBride has a team-high 37 receptions for 347 receiving yards, and two touchdowns. Defensively, Mack Wilson has a team-high 50 total tackles (28 of them solo), while Josh Sweat leads the team in sacks, with 5.0, while Dadrion Taylor-Demerson has two interceptions.

Green Bay Packers Preview

The Green Bay Packers have a 3-1-1 record this season and are sitting first in the NFC North. They are 2-3 ATS, 1-3-1 in Over/Under and have a 3-0 home record and a 0-1-1 away record. The Packers are coming off a 27-18 home win against the Cincinnati Bengals and will face the Cardinals, Steelers and the Panthers next.

Offensively, the Packers average 26.2 points per game, ranking 8th in the NFL, while defensively, they allow 20.4 points per game, which is 10th. Green Bay averages 359.6 total yards per game (237.4 passing and 122.2 rushing), while allowing 280.2 total yards per game (73.0 rushing and 207.2 passing).

Jordan Love leads the Packers with 1259 passing yards with 70.1% completed passes and 9 touchdowns. Josh Jacobs leads the team in rushing yards with 359, while Tucker Kraft has a team-high 18 receptions for 268 receiving yards, and three touchdowns. Defensively, Quay Walker has a team-high 50 total tackles (27 of them solo), while Rashan Gary leads the team in sacks, with 4.5, while Xavier McKinney and Evan Williams each have one interception.

Green Bay Packers @ Arizona Cardinals Betting Trends: Week 7

Why the Arizona Cardinals will win

Why the Green Bay Packers will win

Total Points Facts

Arizona Cardinals Player Prop Facts

Green Bay Packers Player Prop Facts

Matchup/League Facts

Packers vs Cardinals Prediction

In their previous meeting last season, the Packers won 34-13 at home, but the Cardinals are 3-2 in their last 5 meetings, and are 3-1 in their last 4 meetings in Arizona. Under is 4-0-1 in their last 5 meetings.  

In this Packers vs Cardinals Prediction, the Packers are coming as -6.5-point road favorites, with the total set at 44.5 points. The Cardinals are on a free fall lately, as they have four consecutive losses after winning their first two games of the season. On the flip side, the Packers have lost only once in their last five games, and are better both offensively and defensively than the Cardinals, winning by an average of 5.8 points per game. I like Green Bay as a road favorite in this spot, so take the Packers and lay the -6.5 points in this one.

Nikos Lagouretos's Pick: Green Bay Packers -6.5

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