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Colts vs Jaguars Prediction 11/1/2026 Today’s NFL Picks

Oct 18, 2026; Indianapolis, Indiana, USA;  Indianapolis Colts running back Jonathan Taylor (28) runs with the ball against Tennessee Titans safety Tony Adams (29) during the second half at Lucas Oil Stadium.  Mandatory Credit: Trevor Ruszkowski-Imagn Images

Oct 18, 2026; Indianapolis, Indiana, USA; Indianapolis Colts running back Jonathan Taylor (28) runs with the ball against Tennessee Titans safety Tony Adams (29) during the second half at Lucas Oil Stadium. Mandatory Credit: Trevor Ruszkowski-Imagn Images

Indianapolis vs Jacksonville Odds and Matchup Info
MATCHUP Indianapolis Colts Jacksonville Jaguars
Team Records 2-5 4-2
Spread +10 -115 -10 -105
Moneyline +380 -500
Total Over 46.5 (-110) Under 46.5 (-110)
Where EverBank Stadium, Jacksonville, FL
When Sunday, November 1, 2026
Time 01:00 PM EST
TV CBS

Colts vs Jaguars Prediction

Indianapolis comes into this matchup on a three game losing streak and they are coming off of a terrible offensive performance against the Vikings. The Colts are 1-3 on the road this year, while the Jaguars are 3-1 at home. Jacksonville has won three of their last four games, but they allowed 34 points against the Texans last week. The Jaguars struggled to get stops in their last game, but they have allowed 17 points or fewer in three of their last four. These two teams are trending in two different directions and the Colts are starting to trade some players, so I will take the Jaguars to cover, but I don’t love this big number.

Indianapolis Colts Betting Preview

The Indianapolis Colts are 2-5 this season after they lost to the Vikings by a score of 16-10 last week. Indianapolis led 10-6 at halftime, but they were shutout in the second half for another disappointing loss. The Colts were out gained by a total of 275-218, went 8-15 on third downs, and lost the turnover battle by a total of 1-0 in the game. Daniel Jones threw for 108 yards and one interception, while Keenan Allen caught three passes for 31 yards. Jonathan Taylor rushed 18 times for 95 yards and one score in the game.

Prior to that loss, Indianapolis lost to the Titans by a score of 26-20 and the Steelers by a score of 34-22. The Colts have scored 22.0 points per game with 180.4 passing yards and 117.6 rushing yards per game, while they have allowed 25.7 points against per game this season. Daniel Jones has thrown for 1,398 yards with four touchdowns and seven interceptions, while Jonathan Taylor has 140 carries for 587 yards and eight scores this season.

Jacksonville Jaguars Betting Preview

The Jacksonville Jaguars are 4-2 this year after they lost to the Texans by a score of 34-31 in their last game. Jacksonville trailed 17-14 at halftime, but they were tied 31-31 in the fourth quarter, before allowing a field goal as time expired for the loss. The Jaguars were out gained by a total of 426-412, went 7-12 on third downs, and tied the turnover battle at one in the game. Trevor Lawrence threw for 306 yards, four touchdowns, and one interception, while Jakobi Meyers caught five passes for 83 yards. Chris Rodriguez Jr rushed 11 times for 55 yards in the loss.

Prior to that game, Jacksonville defeated the Eagles by a score of 19-17 and the Bengals by a score of 22-17. The Jaguars have scored 25.7 points per game with 234.8 passing yards and 112.8 rushing yards per game, while they have allowed 17.3 points against per game this season. Trevor Lawrence has thrown for 1,480 yards with 14 touchdowns and four interceptions, while Parker Washington has 26 catches for 416 yards and four scores this year.

Why the Jacksonville Jaguars will win

Total Points Facts

Jacksonville Jaguars Player Prop Facts

Indianapolis Colts Player Prop Facts

Matchup/League Facts

David Racey's Pick: Jaguars -10

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