Cincinnati Bengals vs Denver Broncos Prediction 9/29/2025 Today’s NFL Picks

Randy Chambers

5 days ago

Sep 21, 2025; Inglewood, California, USA; Denver Broncos wide receiver Courtland Sutton (14) reaches for a long pass 4th down in the second half against the Los Angeles Chargers at SoFi Stadium. Mandatory Credit: Jayne Kamin-Oncea-Imagn Images

Cincinnati (2-1) vs Denver (1-2)

September 29, 2025 at 08:15 PM EDT

The Line: Betting Odds: Denver -7 — Over/Under: +44.5

The Cincinnati Bengals and Denver Broncos meet Monday in NFL action at Empower Field. Here’s a Cincinnati Bengals vs Denver Broncos Prediction. This article will include a Cincinnati Bengals vs Denver Broncos Pick.

With the Pittsburgh Steelers beating the Minnesota Vikings on Monday, there is pressure on the Bengals to keep pace in a tough AFC North. For the Broncos, the Chargers suffered a disappointing loss at the New York Giants, and this is their chance to move up a game.

Cincinnati Bengals Betting Preview

The Cincinnati Bengals beat the Jaguars, lost to the Vikings, and they play the Lions next. The Cincinnati Bengals have won 7 of their last 8 games. Jake Browning is completing 67.8 percent of his passes for 381 yards, 3 touchdowns, and 5 interceptions. Ja’Marr Chase and Tee Higgins have combined for 345 receiving yards and 2 touchdowns, while Noah Fant has 12 receptions.

The Cincinnati Bengals ground game is averaging 49 yards per contest, and Chase Brown leads the way with 93 yards and 1 touchdown. Defensively, Cincinnati is allowing 30.3 points and 359.7 yards per game. Jordan Battle leads the Cincinnati Bengals with 23 tackles, Trey Hendrickson has 2 sacks and DJ Turner II has 1 interception.

Denver Broncos Betting Preview

The Denver Broncos lost to the Colts and Chargers, and they play the Eagles next. The Denver Broncos have won 6 of their last 10 games. Bo Nix is completing 64.2 percent of his passes for 535 yards, 5 touchdowns, and 3 interceptions. Courtland Sutton and Troy Franklin have combined for 326 receiving yards and 3 touchdowns, while Marvin Mims Jr. has 6 receptions.

The Denver Broncos ground game is averaging 129 yards per contest, and J.K. Dobbins leads the way with 222 yards and 3 touchdowns. Defensively, Denver is allowing 1.3 points and 327.3 yards per game. Talanoa Hufanga leads the Denver Broncos with 27 tackles, Nik Bonitto has 3 sacks and Brandon Jones has 1 interception.

Cincinnati Bengals @ Denver Broncos Betting Trends: Week 4

Why the Denver Broncos will win

The Broncos have won each of their last nine September games against the Bengals.
The Bengals have lost three of their last four Monday games against teams that held a losing record.
The home team has covered the spread in eight of the Broncos’ last nine games.
The Bengals have failed to cover the spread in each of their last three road games.
The Bengals have lost the first quarter in each of their last three games at Empower Field at Mile High against teams that held a losing record.
The Bengals have lost the first half in four of their last five Week 4 games against AFC opponents.

Why the Cincinnati Bengals will win

The Bengals have won each of their last six games against AFC opponents.
The Broncos have lost three of their last four September games as favorites.
The Bengals have covered the spread in 12 of their last 13 games against teams that held a losing record.
The Broncos have failed to cover the spread in seven of their last eight September games as home favorites.
The Broncos have lost the first half in each of their last three September games against AFC North opponents.
The Broncos have lost the first quarter in three of their last four September games against AFC North opponents.

Total Points Facts

Eight of the Broncos’ last nine September games at Empower Field at Mile High have gone UNDER the total points line.
Seven of the Bengals’ last eight games as underdogs following a road loss have gone UNDER the total points line.

Denver Broncos Player Prop Facts

J.K. Dobbins has scored a touchdown in each of his last five September appearances with his team as a favorite.
J.K. Dobbins has recorded 50+ rushing yards in 11 of his last 12 regular season appearances with his team as a favorite.
J.K. Dobbins has recorded 59+ rushing and receiving yards in each of his last seven regular season appearances against AFC opponents.
J.K. Dobbins has scored the last touchdown in four of his last five regular season appearances with his team as a favorite against AFC opponents.
Evan Engram has recorded 21+ receiving yards in 16 of his last 17 appearances following a loss.
Bo Nix has recorded 22+ completions in five of the Broncos’ last six regular season games against AFC opponents.
Heading into Week 4, Courtland Sutton ranks T1st in the AFC for 20+ yard receiving touchdowns (2) this season.

Cincinnati Bengals Player Prop Facts

Samaje Perine has recorded 17+ rushing yards in each of his last four appearances with the Bengals as road underdogs.
Samaje Perine has recorded 26+ rushing and receiving yards in each of his last four appearances with the Bengals as road underdogs against AFC opponents.
Tanner Hudson has recorded 10+ receiving yards in each of his last eight appearances with his team as an underdog.
Ja’Marr Chase has scored two or more touchdowns in three of the Bengals’ last four games as underdogs.
Tee Higgins has scored at least one touchdown in eight of his last 10 appearances against AFC opponents.
Heading into Week 4, Ryan Rehkow ranks 1st amongst qualified players for gross average yards per punt (54.0) this season.

Matchup/League Facts

Heading into Week 4, the Broncos rank T1st in the NFL in sacks (12.0) this season.
Heading into Week 4, the Broncos rank T1st in the NFL in 4th down percentage against (0.0%) this season.
Heading into Week 4, the Bengals rank 1st in the NFL in total punt yards (810) this season.
Heading into Week 4, the Bengals rank 1st in the NFL in average yards per punt (54.0) this season.