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Buffalo Bills vs Jacksonville Jaguars Prediction 1/11/2026 Today’s NFL Picks

Jacksonville Jaguars wide receiver Jakobi Meyers (3) rushes for yards against Tennessee Titans safety Sanoussi Kane (42) during the fourth quarter of an NFL football matchup at EverBank Stadium, Sunday, Jan. 4, 2026, in Jacksonville, Fla. The Jaguars defeated the Titans 41-7, capturing the AFC South title. [Corey Perrine/Florida Times-Union]

Jacksonville Jaguars wide receiver Jakobi Meyers (3) rushes for yards against Tennessee Titans safety Sanoussi Kane (42) during the fourth quarter of an NFL football matchup at EverBank Stadium, Sunday, Jan. 4, 2026, in Jacksonville, Fla. The Jaguars defeated the Titans 41-7, capturing the AFC South title. [Corey Perrine/Florida Times-Union]

MATCHUP Buffalo Bills Jacksonville Jaguars
Team Records 12-5 13-4
Where EverBank Stadium, Jacksonville, FL
When Sunday, January 11, 2026
Time 01:00 PM EST
TV CBS
In this article, we will formulate a Bills vs Jaguars Prediction for this AFC Wild Card game on Sunday, January 11th. Let’s take a look at the prediction for this NFL matchup.

Jacksonville Jaguars Preview


The Jacksonville Jaguars have a 13-4 record this season and finished first in the AFC South. They are 12-5 ATS, 10-7 in Over/Under and have a 7-2 home record and a 6-2 away record. The Jaguars are coming off a 41-7 home win against the Tennessee Titans.

Offensively, the Jaguars average 27.9 points per game, ranking 6th in the NFL, while defensively, they allow 19.8 points per game, which is 8th. Jacksonville averages 337.4 total yards per game (222.3 passing and 115.1 rushing), while allowing 303.6 total yards per game (85.6 rushing and 218.0 passing).

Trevor Lawrence leads the Jaguars with 4007 passing yards with 60.9% completed passes and 29 touchdowns. Travis Etienne leads the team in rushing yards with 1107, while Parker Washington has a team-high 58 receptions for 847 receiving yards, and five touchdowns. Defensively, Foyesade Oluokun has a team-high 143 total tackles (69 of them solo), while Josh Hines-Allen leads the team in sacks, with 8, while Devin Lloyd and Antonio Johnson have five interceptions each.

Buffalo Bills Preview


The Buffalo Bills have a 12-5 record this season and finished second in the AFC East. They are 8-9 ATS, 9-8 in Over/Under and have a 7-2 home record and a 5-3 away record. The Bills are coming off a 35-8 home win against the New York Jets.

Offensively, the Bills average 28.3 points per game, ranking 4th in the NFL, while defensively, they allow 21.5 points per game, which is 12th. Buffalo averages 376.3 total yards per game (216.6 passing and 159.6 rushing), while allowing 293.1 total yards per game (136.2 rushing and 156.9 passing).

Josh Allen leads the Bills with 3668 passing yards with 69.3% completed passes and 25 touchdowns. James Cook leads the team in rushing yards with 1621, while Khalil Shakir has a team-high 72 receptions for 719 receiving yards, and four touchdowns. Defensively, Cole Bishop has a team-high 85 total tackles (53 of them solo), while Gregory Rousseau leads the team in sacks, with 7, while Cole Bishop has three interceptions.

Buffalo Bills @ Jacksonville Jaguars Betting Trends: Wild Card Round


Why the Jacksonville Jaguars will win

Why the Buffalo Bills will win

Total Points Facts

Jacksonville Jaguars Player Prop Facts

Buffalo Bills Player Prop Facts

Matchup/League Facts

Bills vs Jaguars Prediction


In this Bills vs Jaguars Prediction, the Bills are coming as -1-point road favorites. Both teams have almost identical overall records this season but the Jaguars have been very strong at home with a 7-2 record and have been red-hot lately, with a perfect 8-0 record both straight up and against the spread in their last 8 games. Buffalo is 5-1 in its last 6 but just 2-3 against the spread and have a weaker defense than the Jaguars and have lost their last three visits in Jacksonville, so the value here lies with the home dog. Take the Jaguars on the moneyline for plus money in this one.

Nikos Lagouretos's Pick: Jacksonville Jaguars ML

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