Bengals vs Bills Prediction 12/7/2025 Today’s NFL Picks

David Racey

19 hours ago

Nov 30, 2025; Pittsburgh, Pennsylvania, USA; Buffalo Bills quarterback Josh Allen (17) looks to pass as Pittsburgh Steelers defensive end Esezi Otomewo (93) attempts to tackle during the second quarter at Acrisure Stadium. Mandatory Credit: Charles LeClaire-Imagn Images

MATCHUP	Cincinnati Bengals	Buffalo Bills
Team Records	4-8	8-4
Spread	+5.5 100	-5.5 -120
Moneyline	+220	-270
Total	Over 53.5 (-112)	Under 53.5 (-108)
Where	Highmark Stadium, Orchard Park, NY
When	Sunday, December 7, 2025
Time	01:00 PM EST
TV	FOX

In this article we will formulate a Bengals vs Bills prediction for this NFL game on Sunday, December 7th at Highmark Stadium in Orchard Park, New York. Let’s take a look at the prediction for this week 14 matchup.

Cincinnati Bengals Betting Preview

The Cincinnati Bengals are 4-8 this season after they defeated Baltimore by a score of 32-14 in their last game. Cincinnati led 12-7 at halftime and 19-14 in the third quarter, but they scored the last 13 points to pull away for the win. The Bengals out gained Baltimore by a total of 382-346, went 8-19 on third downs, and won the turnover battle by a total of 5-1 in the game. Joe Burrow went 24-46 for 261 yards and two touchdowns, while Chase Brown rushed 15 times for 78 yards. Ja’Marr Chase led the receivers with seven receptions for 110 yards in the win.

Prior to that game, Cincinnati lost to the Patriots by a score of 26-20 and the Steelers by a score of 34-12. The Bengals have lost four of their last five games and they are currently third in the AFC North standings. Cincinnati has scored 23.3 points per game with 224.8 passing yards and 88.5 rushing yards per game, while they have allowed 31.2 points against per game this season. Joe Burrow has thrown for 450 yards, four touchdowns, and zero interceptions, while Ja’Marr Chase has 86 catches for 971 yards and five scores this season.

Buffalo Bills Betting Preview

The Buffalo Bills are 8-4 this year after they defeated Pittsburgh by a score of 26-7 last week. Buffalo trailed 7-3 at halftime, but they scored 23 points in the second half and pitched a shutout for the lopsided win. The Bills out gained Pittsburgh by a total of 372-166, went 8-15 on third downs, and tied the turnover battle at two in the game. Josh Allen went 15-23 for 123 yards, one touchdown, and one interception, while James Cook rushed 32 times for 144 yards. Cook also led the receivers with three catches for 33 yards in the win.

Prior to that game, Buffalo lost to the Texans by a score of 23-19, but did beat the Buccaneers by a score of 44-32 before that. The Bills have alternated wins and losses over their last five games and they are currently second in the AFC East standings. Buffalo has scored 28.1 points per game with 225.3 passing yards and 155.7 rushing yards per game, while they have allowed 21.6 points against per game this season. Josh Allen has thrown for 2,832 yards, 19 touchdowns, and 10 interceptions, while James Cook has rushed 231 times for 1,228 yards and eight scores this year.

Why the Buffalo Bills will win

The Bills have won each of their last 17 home games following a road win.
The Bengals have lost each of their last seven Sunday games.
The Bengals have failed to cover the spread in seven of their last eight games when playing with a rest advantage.
The home team has covered the spread in four of the Bills’ last five games.
The Bengals have lost the first quarter in four of their last five road games.
The Bengals have lost the first half in six of their last seven Sunday games as underdogs.

Total Points Facts

Seven of the Bengals’ last eight games against AFC East opponents have gone UNDER the total points line.
Seven of the Bills’ last eight games as favorites following a road win have gone OVER the total points line.

Buffalo Bills Player Prop Facts

Josh Allen has scored two touchdowns in three of the Bills’ last four games at Highmark Stadium with a total points line of at least 50.0.
Josh Allen has recorded 21+ completions in seven of the Bills’ last eight games following a road win.
Josh Allen has recorded 253+ passing yards in 16 of the Bills’ last 20 games with a total points line of at least 50.0.
Josh Allen has recorded 40+ rushing yards in each of the Bills’ last four Sunday games as home favorites.
James Cook has scored at least one touchdown in eight of the Bills’ last nine games against teams that held a losing record.
Gabriel Davis has recorded 25+ receiving yards in seven of his last eight appearances with the Bills as favorites in games with a total points line of at least 50.0.
James Cook has recorded 114+ rushing and receiving yards in four of the Bills’ last five home games.
Heading into Week 14, James Cook has recorded the equal-most rushing attempts in a single game this season (32 vs Steelers, Week 13).

Cincinnati Bengals Player Prop Facts

Joe Burrow has recorded 26+ completions in each of his last four December road appearances.
Ja’Marr Chase has scored at least one touchdown in four of the Bengals’ last five games played as underdogs on the East Coast.
Joe Flacco has recorded 254+ passing yards in each of his last six December appearances.
Samaje Perine has recorded 22+ rushing yards in five of his last six appearances with the Bengals as underdogs against AFC opponents.
Samaje Perine has recorded 33+ rushing and receiving yards in each of his last four December appearances with the Bengals as underdogs.
Noah Fant has recorded 12+ receiving yards in each of his last 11 December appearances with his team as an underdog.
Heading into Week 14, Joe Flacco has recorded the most passing yards in a single game this season (470 vs Bears, Week 9).

Matchup/League Facts

Heading into Week 14, the Bills rank 1st in the NFL in passing yards allowed per game (163.2) this season.
Heading into Week 14, the Bills rank 32nd in the NFL in average punt return (5.2 yards) this season.
Heading into Week 14, the Bengals rank 32nd in the NFL in points allowed per game (31.2) this season.
Heading into Week 14, the Bengals rank 32nd in the NFL in yards allowed per game (410.0) this season.

Bengals vs Bills Prediction

Cincinnati comes into this matchup with plenty of momentum after beating Baltimore last week and they are a new team with Burrow back from injury. The Bengals have one of the better passing attacks in the NFL, but the defense is below average at best. Buffalo has been very inconsistent in their last five games, but they should have no problem moving the ball here. I do think we will see plenty of scoring in this game, especially as Cincinnati has allowed at least 34 points in three of their last five games, but I trust the Buffalo defense to make a few more plays. Take the Bills to cover here.

David Racey is 79-58 (58%) in the NFL this season and he is currently #2 on the NFL Leaderboard. Click here for his premium plays for this week!