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Arizona Cardinals vs Houston Texans Prediction 12/14/2025 Today’s NFL Picks

Nov 19, 2023; Houston, Texas, USA; Houston Texans cornerback Steven Nelson (21) deflects a pass intended for Arizona Cardinals wide receiver Marquise Brown (2) during the fourth quarter at NRG Stadium. Mandatory Credit: Troy Taormina-Imagn Images

Nov 19, 2023; Houston, Texas, USA; Houston Texans cornerback Steven Nelson (21) deflects a pass intended for Arizona Cardinals wide receiver Marquise Brown (2) during the fourth quarter at NRG Stadium. Mandatory Credit: Troy Taormina-Imagn Images

MATCHUP Arizona Cardinals Houston Texans
Team Records 3-10 8-5
Spread +10 -115 -10 -105
Moneyline +440 -600
Total Over 42.5 (-105) Under 42.5 (-115)
Where NRG Stadium, Houston, TX
When Sunday, December 14, 2025
Time 01:00 PM EST
TV FOX
In this article, we will formulate a Cardinals vs Texans Prediction for this NFL Week 13 game on Sunday, December 14th. Let’s take a look at the prediction for this NFL matchup.

Houston Texans Preview


The Houston Texans have an 8-5 record this season and are sitting second in the AFC South. They are 7-6 ATS, 3-9-1 in Over/Under and have a 4-2 home record and a 4-3 away record. The Texans are coming off a 20-10 away win against the Kansas City Chiefs and will face the Raiders and Chargers next.

Offensively, the Texans average 21.8 points per game, ranking 20th in the NFL, while defensively, they allow 16 points per game, which is 1st. Houston averages 322.2 total yards per game (216.5 passing and 105.7 rushing), while allowing 266.3 total yards per game (94.3 rushing and 172 passing).

C.J. Stroud leads the Texans with 2181 passing yards with 64.3% completed passes and 12 touchdowns. Woody Marks leads the team in rushing yards with 554, while Nico Collins has a team-high 61 receptions for 916 receiving yards, and four touchdowns. Defensively, Azeez Al-Shaair has a team-high 84 total tackles (39 of them solo), while Will Anderson and Danielle Hunter lead the team in sacks, with 10.5 and 11 each.

Arizona Cardinals Preview


The Arizona Cardinals have a 3-10 record this season and are sitting fourth in the NFC West. They are 6-7 ATS, 8-5 in Over/Under and have a 1-6 home record and a 2-4 away record. The Cardinals are coming off a 17-45 home loss against the Los Angeles Rams and will face the Falcons and Bengals next.

Offensively, the Cardinals average 21.7 points per game, ranking 21st in the NFL, while defensively, they allow 26.8 points per game, which is 26th. Arizona averages 335.5 total yards per game (238.7 passing and 96.8 rushing), while allowing 347.4 total yards per game (123.1 rushing and 224.3 passing).

Jacoby Brissett leads the Cardinals with 2459 passing yards with 66.2% completed passes and 15 touchdowns. Zonovan Knight leads the team in rushing yards with 271, while Trey McBride has a team-high 93 receptions for 937 receiving yards, and eight touchdowns. Defensively, Budda Baker has a team-high 93 total tackles (41 of them solo), while Josh Sweat leads the team in sacks, with 11.

Arizona Cardinals @ Houston Texans Betting Trends: Week 15


Why the Houston Texans will win

Why the Arizona Cardinals will win

Total Points Facts

Houston Texans Player Prop Facts

Arizona Cardinals Player Prop Facts

Matchup/League Facts

Cardinals vs Texans Prediction


In this Cardinals vs Texans Prediction, the Texans are coming as -9.5-point home favorites. The Texans have been the far better team this season, as they have a better record, they have been very strong at home and are coming into this matchup red-hot, with five consecutive wins and are 4-1 against the spread. On the flip side, Arizona has been on a free fall lately, with a 1-10 record in its last 11 games and 1-4 against the spread in its last 5. The Texans have the best defense in the league and have won both previous home meetings against the Cardinals. Take Houston and lay the -9.5 at home in this one.

Nikos Lagouretos's Pick: Houston Texans -9.5

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