49ers vs Giants Prediction 11/2/2025 Today’s NFL Picks

David Racey

4 weeks ago

Oct 19, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (center) carries the ball against Atlanta Falcons safety Xavier Watts (31) during the second quarter at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images

MATCHUP	San Francisco 49ers	New York Giants
Team Records	6-3	2-7
Where	MetLife Stadium, East Rutherford, NJ
When	Sunday, November 2, 2025
Time	01:00 PM EST
TV	CBS

In this article we will formulate a 49ers vs Giants prediction for this NFL game on Sunday, November 2nd at MetLife Stadium in East Rutherford, New Jersey. Let’s take a look at the prediction for this week 9 matchup.

San Francisco 49ers Betting Preview

The San Francisco 49ers are 5-3 this year after they lost to Houston by a score of 26-15 in their last game. San Francisco trailed 16-7 at halftime and only managed to score eight points in the second half in the loss. The 49ers were out gained by a total of 475-223, went 3-9 on third downs, and tied the turnover battle at one in the game. Mac Jones went 19-32 for 193 yards, two touchdowns, and one interception, while Christian McCaffrey rushed eight times for 25 yards. Jauan Jennings led the receivers with four catches for 45 yards in the loss. The SF defense recorded zero sacks and three tackles for loss in the game.

Prior to that game, San Francisco defeated the Falcons by a score of 20-10, but did lose to the Buccaneers by a score of 30-19 before that. The 49ers have alternated wins and losses over their last six games and they are currently third in the NFC West standings. San Francisco has scored 20.0 points per game with 259.3 passing yards and 89.4 rushing yards per game, while they have allowed 20.5 points against per game this season. Mac Jones has thrown for 1,597 yards, eight touchdowns, and five interceptions, while Christian McCaffrey has 490 rushing yards, 559 receiving yards, and six total touchdowns this year.

New York Giants Betting Preview

The New York Giants are 2-6 this season after they lost to Philadelphia by a score of 38-20 in their last game. New York trailed 21-10 at halftime and they were outscored 17-10 in the second half for the loss. The Giants were out gained by a total of 427-246, went 5-12 on third downs, and tied the turnover battle at zero in the game. Jaxson Dart went 14-24 for 193 yards and one touchdown, while Tyrone Tracy Jr rushed 10 times for 39 yards. Wan’Dale Robinson led the receivers with three catches for 48 yards in the loss. The NY defense recorded four sacks and three tackles for loss in the game.

Prior to that game, New York lost to the Broncos by a score of 33-32, but did beat the Eagles by a score of 34-17 before that. The Giants have lost three of their last four games and they are currently last in the NFC East standings. New York has scored 21.6 points per game with 207.3 passing yards and 118.0 rushing yards per game, while they have allowed 26.9 points against per game this season. Jaxson Dart has thrown for 984 yards, eight touchdowns, and three interceptions, while Wan’Dale Robinson has 38 receptions for 494 yards and two scores this season.

Why the San Francisco 49ers will win

The Giants have lost each of their last seven games following a Division game.
The 49ers have won each of their last six road games against NFC East opponents on a losing streak.
The 49ers have covered the spread in nine of their last 10 games against NFC East opponents.
The Giants have failed to cover the spread in five of their last six November games against NFC opponents.
The Giants have lost the first quarter in four of their last five games against NFC West opponents.
The 49ers have won the first half in each of their last seven November games against NFC East opponents.

Total Points Facts

Five of the 49ers’ last six road games against NFC opponents have gone OVER the total points line.
Five of the Giants’ last six Week 9 home games have gone OVER the total points line.

New York Giants Player Prop Facts

Jaxson Dart has scored a touchdown in each of the Giants’ last four games as underdogs against teams that held a winning record.
Tyrone Tracy has recorded 35+ rushing and receiving yards in each of his last 12 Sunday appearances with the Giants as underdogs.
Tyrone Tracy has recorded 23+ rushing yards in each of his last eight Sunday home appearances.
Jaxson Dart has recorded 195+ passing yards in three of the Giants’ last four games as underdogs.
Darius Slayton has recorded 40+ receiving yards in four of the Giants’ last five November games as home underdogs against NFC opponents.
Heading into Week 9, Russell Wilson has recorded the most passing yards in a single game this season (450 vs Cowboys, Week 2).

San Francisco 49ers Player Prop Facts

Christian McCaffrey has scored a touchdown in six of his last seven appearances against NFC East opponents.
Brian Robinson has recorded 13+ rushing yards in 20 of his 21 previous Sunday appearances with his team as a favorite.
Mac Jones has recorded 220+ passing yards in each of his last six road appearances against conference opponents.
Demarcus Robinson has recorded 37+ receiving yards in nine of his last 10 road appearances against NFC opponents.
Brian Robinson has recorded 22+ rushing and receiving yards in 23 of his 24 previous appearances following a loss.
Brock Purdy has recorded 22+ completions in each of his last four appearances.
Heading into Week 9, Eddy Pineiro has recorded the equal-most made field goals without a failed attempt this season (17).

Matchup/League Facts

Heading into Week 9, the Giants rank 32nd in the NFL in 4th down percentage against (87.5%) this season.
Heading into Week 9, the Giants have given up the equal largest lead to win a game this season – 19 points vs Broncos.
Heading into Week 9, the 49ers have recorded the equal-most wins by a margin of five points or less this season (4).
Heading into Week 9, the 49ers rank 2nd in the NFL in passing yards per game (259.3) this season.