49ers at Cardinals Prediction - NFL Picks 12/17/23

Arizona Cardinals (3-10) vs San Francisco 49ers (10-3)

Game Info: Sunday, December 17, 2023 at 4:05 pm (State Farm Stadium)

Betting Odds: Arizona Cardinals +12.5 -- Over/Under: 48.5 Click Here for the Latest Odds

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The San Francisco 49ers will head down to Phoenix to face the Arizona Cardinals in divisional action this Sunday from State Farm Stadium on CBS. San Francisco comes in as 12.5-point favorites, with the total currently hovering 48.5. Stay tuned for our Cardinals vs 49ers prediction.

San Francisco 49ers Preview

San Francisco improved to 10-3 after defeating Seattle at home, 28-16. The Niners found the endzone in all four quarters during the win over the Seahawks, and they’ll look to extend their lead atop the NFC this Sunday. The San Fran offense is scoring 29.2 ppg, while passing for 273.8 ypg, rushing for 123.9  ypg, and converting 47.5% of their third downs.

49ers Player Props

  • Brock Purdy went for a season-high 368 yards and a pair of touchdowns in the win over Seattle. The former ISU quarterback continues to make his case for the MVP award, and a strong close to the season may just be all he needs at this point. Purdy has passed for 3,553 yards, with 25 touchdowns to seven interceptions thru twelve games. 
  • Christian McCaffrey also hit a season-best with 145 yards versus the Seahawks, and he leads the Niners with 1,177 yards on 226 touches.?
  • Deebo Samuel scored twice against Seattle, and the versatile weapon is up to 739 receiving yards and 161 rushing yards for the season.
  • Brandon Aiyuk went for 126 yards last weekend, and he leads San Francisco in receptions (56) and receiving yards (1053). 
  • The San Francisco defense is allowing 15.8 points per game.   

Arizona Cardinals Preview

Arizona moved to 3-10 after defeating Pittsburgh on the road, 24-10. The Cardinals traveled and picked up an impressive victory over the Steelers, and they’ll attempt to shake up the NFC with a strong effort Sunday. The Arizona offense is scoring 17.7 ppg, while passing for 191.9 ypg, rushing for 123.9 ypg, and converting 35.3% of their third downs.

Cardinals Player Props

  • Kyler Murray managed last week’s contest well, protecting the football, while passing for 145 yards and a score versus the Steelers. The former OU quarterback has simply made the team more competitive down the stretch, and he’ll attempt to provide some magic here against San Fran. Murray has passed for 864 yards, with three touchdowns to two interceptions through three games. 
  • James Conner returned to the Steel City then punished his former team with 105 yards and a pair of scores, and he leads the Cardinals in rushing yards (499). 
  • Trey McBride has turned into a bright spot at tight end, and after bringing in eight catches for 89 yards in the win over Pittsburgh, he leads ARZ in receptions (56) and receiving yards (610).
  • The Atlanta defense is allowing 25.5 points per game.   

 

San Francisco vs Arizona Trends

  • SF is 7-6 against the spread, with a 6-6-1 O/U record. 
  • ARZ is 7-6 ATS, with a 7-6 over/under record.

San Francisco vs Arizona Prediction 

Arizona has looked visibly better with Kyler Murray under center over the past four weeks, but San Francisco has been on a mission and picked up steam during the same time span. The Cardinals have played hard under Jonathan Gannon all season, so an extended effort from them wouldn’t be surprising at all, even at 3-10, but there’s also a chance the Niners make this one ugly, and they’re more trustworthy than the hosts. Give the Over a look in case San Francisco comes out and does the heavy lifting, but back them to beat the Cardinals by two scores Sunday.

Corey’s Pick 49ers TO COVER

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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