Giants vs Cardinals Prediction - NFL Picks 9/17/23

Arizona Cardinals (0-1) vs New York Giants (0-1)

Game Info: Sunday, September 17, 2023 at 4:05 pm (State Farm Stadium)

Betting Odds: Arizona Cardinals +4 -- Over/Under: 40 Click Here for the Latest Odds

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The New York Giants will play the Arizona Cardinals in Week 2 on Sunday afternoon at State Farm Stadium in Glendale, Arizona. The Giants got blown out in their first game of the season and will try to score their first points of the year, while Arizona lost a thrilling game with the Commanders to open their season. 

Giants Preview

The New York Giants are 0-1 this season after they lost to the Dallas Cowboys by a score of 40-0 on Sunday Night Football. New York had some success on their first drive, but their field goal attempt was blocked and returned for a touchdown. The Giants trailed 26-0 at the half and weren’t able to generate any points in the second half. New York was out gained by a total of 265-171 and they turned the ball over three times in the loss. The Giants threw for 63 yards and rushed for 108 yards, while going 5-16 on third downs and 3-5 on fourth downs. Daniel Jones threw for 104 yards and two interceptions, while also adding 43 rushing yards. The Giants were sacked seven times for a loss of 47 yards. Saquon Barkley rushed 12 times for 51 yards, while Darren Waller caught three passes for 36 yards in the game. The New York defense allowed 143 passing yards and 122 rushing yards, but didn’t generate any sacks or turnovers. 

Cardinals Preview

The Arizona Cardinals are 0-1 this year after they lost to Washington by a score of 20-16 last week. Arizona led this game 13-10 at halftime and 16-10 going into the fourth quarter, but was out scored 10-0 in the final quarter for the loss. Arizona was out gained by a total of 248-210 but they did win the turnover battle by a total of 3-2. The Cardinals threw for 114 passing yards and rushed for 96 yards, while going 4-14 on third downs and 0-1 on fourth down. Arizona committed nine penalties for 122 yards. Joshua Dobbs threw for 132 yards for the Cardinals in the loss. James Conner rushed for 62 yards, while Rondale Moore caught three passes for 33 yards in the game. Marquise Brown added three catches for 28 yards and one rush for 29 yards. The Arizona defense allowed 156 passing yards and 92 rushing yards, but did force three turnovers in the game. 

Arizona Cardinals Team Facts

  • The Cardinals have lost each of their last eight Sunday games at State Farm Stadium.
  • The Cardinals have covered the spread in nine of their last 10 games against NFC East opponents.
  • The Cardinals have scored the first touchdown in each of their last four games against the Giants.
  • The Cardinals have lost the first quarter in five of their last seven games at State Farm Stadium against teams that held a losing record.
  • The favorites have won the first half in seven of the Cardinals' last eight Week 2 games.

New York Giants Team Facts

  • The Giants have lost four of their last five September games as favorites.
  • The Giants have covered the spread in seven of their last eight games following a home loss.
  • The Giants have scored the first touchdown in seven of their last eight Sunday games as favorites.
  • The Giants have lost the first quarter in seven of their last eight games against NFC opponents.
  • The Giants have lost the first half in each of their last seven September road games against NFC opponents.

Arizona Cardinals Player Prop Facts

  • Marquise Brown has scored a touchdown in each of his three previous home appearances against NFC East opponents.
  • Marquise Brown has recorded 46+ receiving yards in each of his last four Sunday home appearances.

New York Giants Player Prop Facts

  • Daniel Jones has thrown four or more touchdowns in two of the Giants' last three Sunday games as road favorites.
  • Daniel Jones has recorded 21+ completions in four of his last five road appearances.
  • Saquon Barkley has scored at least one touchdown in five of his last six road appearances.
  • Daniel Jones has recorded 213+ passing yards in each of the Giants' last three games as road favorites.
  • Saquon Barkley has recorded 21+ receiving yards in each of his last four road appearances against NFC opponents.
  • Daniel Jones has recorded 35+ rushing yards in each of the Giants' last five games following a loss.
  • Saquon Barkley ranked 4th in the NFL in Rushing Yards (1312) last season

Matchup/League Facts

  • The Cardinals ranked 24th in the NFL in passing yards allowed per game (230.3) last season
  • The Cardinals ranked T23rd in the NFL in sacks (36.0) last season
  • The Giants ranked T2nd in the NFL in fumbles recovered (13) last season
  • The Giants ranked 4th in the NFL in rushing yards per game (148.2) last season


The Giants played very poorly in their first game of the season, but they will get the chance to bounce back against an Arizona team that is missing their starting quarterback. The Cardinals had a lead in the fourth quarter against Washington, but they didn’t generate much offense in the second half, only scoring three points. I think we are going to see a much better effort from the Giants in this contest, as they really couldn’t play much worse. The Giants defense held Dallas to only 265 total yards and will play an Arizona team that is definitely a downgrade from the Dallas offense. Take the Giants to bounce back with a nice road win here. 

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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