Cowboys at 49ers Prediction - NFL Picks 1/22/23

San Francisco 49ers (14-4) vs Dallas Cowboys (13-5)

Game Info: Sunday, January 22, 2023 at 6:30 pm (Levi's Stadium)

Betting Odds: San Francisco 49ers -4 -- Over/Under: 46 Click Here for the Latest Odds

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The Dallas Cowboys and San Francisco 49ers clash Sunday in NFL Divisional Playoff action at Levi's Stadium. Let’s dive into the odds, injuries, matchup history and make a prediction for this game.

Cowboys vs 49ers Odds

The 49ers are 4 point favorites and have a ML price of -200. The over / under is sitting at 46.5 points.

Cowboys vs 49ers Injuries

The Cowboys will be without tackle Jason Peters. The Cowboys have questionable players in Jayron Kearse, Trayvon Mullen and Matt Farniok. The 49ers will be without cornerback Ambry Thomas and defensive lineman Hassan Ridgeway. Wide receiver Jauan Jennings is probable despite an ankle injury.

Recent Meeting

The 49ers beat the Cowboys 23-17 about a year and a week ago. Also, a playoff game, the 49ers jumped out to a 13-0 lead and never looked back. The Cowboys have won 5 of the last 7 meetings against the 49ers, a span that dates back to 2008.

Cowboys vs 49ers Trends

The Cowboys are 12-5-1 ATS in their last 18 road games and 1-4 ATS in their last 5 playoff games. The 49ers are 12-2 ATS in their last 14 home games and 22-8 ATS in their last 30 games overall. The under is 4-1 in Cowboys last 5 road games. The over is 4-0 in 49ers last 4 games overall. The road team is 4-1-1 ATS in their last 6 meetings.

Randy’s Free Pick

The 49ers should be favored because they're at home, they've been more consistent, and they've been covering machines these last two seasons. It's hard to make a case against the consistent 49ers. With that said, the Cowboys are far from a pushover and while I don't want to put too much stock into last week, they had a certain pep in their step. The Cowboys have also built a reputation the last couple of years of being road warriors, going into tough venues and giving opponents serious scares. This has the feel of being a back and forth, close game that could be decided on a late field goal. I'll take my chances with the Cowboys on the road and the free points.

Randy’s Pick Dallas Cowboys +4

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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