Los Angeles Chargers at San Francisco 49ers - 11/13/22 NFL Picks and Prediction

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The San Francisco 49ers and Los Angeles Chargers clash Sunday night in week 10 NFL action at Levi’s Stadium. The San Francisco 49ers look to get a game above a .500 record. The Los Angeles Chargers look for a win after winning 4 of their last 5 games. 

The San Francisco 49ers have won 2 of their last 3 home games. Jimmy Garoppolo is completing 66.7 percent of his passes for 1,691 yards, 11 touchdowns and 4 interceptions. Brandon Aiyuk and Deebo Samuel have combined for 870 receiving yards and 6 touchdowns, while George Kittle has 28 receptions. The San Francisco 49ers ground game is averaging 119.5 yards per contest, and Samuel leads the way with 138 yards and 1 touchdown. Defensively, San Francisco is allowing 18.4 points and 285.9 yards per game. Fred Warner leads the San Francisco 49ers with 62 tackles, Nick Bosa has 8.5 sacks and Talanoa Hufanga has 3 interceptions.

The Los Angeles Chargers have won 3 straight road games. Justin Herbert is completing 66.4 percent of his passes for 2,254 yards, 13 touchdowns and 5 interceptions. Mike Williams and Austin Ekeler have combined for 876 receiving yards and 7 touchdowns, while Joshua Palmer has 34 receptions. The Los Angeles Chargers ground game is averaging 89.1 yards per contest, and Ekeler leads the way with 427 yards and 6 touchdowns. Defensively, Los Angeles is allowing 25.8 points and 352.3 yards per game. Derwin James Jr. leads the Los Angeles Chargers with 72 tackles, Khalil Mack has 6 sacks and Bryce Callahan has 2 interceptions.

The Chargers are 4-0 ATS in their last 4 road games and 2-7 ATS in their last 9 games in Week 10. The 49ers are 6-1 ATS in their last 7 home games and 14-6 ATS in their last 20 games overall. The over is 10-4 in Chargers last 14 games overall. The under is 4-1 in 49ers last 5 home games. The road team is 4-1 ATS in their last 5 meetings.

The San Francisco 49ers should be the favorite at home as they’re the more balanced team, and they’ve had an extra week to prepare for this game. However, this line feels a bit thick for a Los Angeles Chargers club that can be explosive offensively and has won 3 straight road games. The Chargers have their flaws, mainly with turnovers and a defense that’s 30th in scoring, but there’s talent, and they’re capable of beating anyone on any given day. I’ll take a shot with the free points.

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

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