San Francisco 49ers at Carolina Panthers - 10/9/22 NFL Picks and Prediction

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The Carolina Panthers and San Francisco 49ers do battle Sunday in a week 5 NFC NFL game at Bank of America Stadium. The Carolina Panthers look to rebound from a 1-3 start. The San Francisco 49ers look to get a game above a .500 record. 

The Carolina Panthers have lost 8 of their last 9 home games. Baker Mayfield is completing 54.7 percent of his passes for 747 yards, 4 touchdowns and 3 interceptions. Robbie Anderson and DJ Moore have combined for 312 receiving yards and 2 touchdowns, while Christian McCaffrey has 19 receptions. The Carolina Panthers ground game is averaging 96.3 yards per contest, and McCaffrey leads the way with 270 yards and 1 touchdown. Defensively, Carolina is allowing 21.3 points and 346 yards per game. Frankie Luvu leads the Carolina Panthers with 32 tackles, Brian Burns has 3 sacks and Derrick Brown has 1 interception.

The San Francisco 49ers have split their last 8 road games. Jimmy Garoppolo is completing 61 percent of his passes for 604 yards, 3 touchdowns and 1 interception. Deebo Samuel and Brandon Aiyuk have combined for 425 receiving yards and 2 touchdowns, while Jauan Jennings has 8 receptions. The San Francisco 49ers ground game is averaging 135.3 yards per contest, and Jeff Wilson Jr. leads the way with 255 yards and 1 touchdown. Defensively, San Francisco is allowing 11.5 points and 234.5 yards per game. Dre Greenlaw leads the San Francisco 49ers with 38 tackles, Nick Bosa has 6 sacks and Talanoa Hufanga has 2 interceptions.

The 49ers are 6-1 ATS in their last 7 vs. NFC and 6-2 ATS in their last 8 games overall. The Panthers are 7-20-1 ATS in their last 28 home games and 3-15 ATS in their last 18 games overall. The under is 10-1 in 49ers last 11 games overall. The under is 5-2 in Panthers last 7 games overall. The 49ers are 1-4 ATS in their last 5 meetings in Carolina and 2-6 ATS in their last 8 meetings.

There’s some value with the Carolina Panthers as home dogs, given the 49ers are on a short week. However, the Panthers haven’t done much well on either side of the ball, they struggle big time offensively and playing at home hasn’t helped much dating back to last season. The San Francisco 49ers are one of the best defensive teams in the league, and they pressure the quarterback. Baker Mayfield, who has had issues with turnovers, is sure to make a mistake or two here. I’ll take the 49ers by a touchdown.

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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