Los Angeles Rams at San Francisco 49ers - 10/3/22 NFL Picks and Prediction

San Francisco 49ers (1-2) vs Los Angeles Rams (2-1)

Game Info: Monday, October 3, 2022 at 8:15 pm (Levi's Stadium)

Betting Odds: San Francisco 49ers -1.5 -- Over/Under: 42.5 Click Here for the Latest Odds

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The Los Angeles Rams will play the San Francisco 49ers in Week 4 of the NFL regular season on Monday Night Football at Levi’s Stadium in Santa Clara, California.

The Los Angeles Rams are 2-1 this season after they defeated Arizona by a score of 20-12 in Week 3. Los Angeles was outgained in total yards in this game but was able to hold Arizona to 6-18 on third down conversions and was able to hold them to field goals in the red zone. The Los Angeles offense is averaging 20.3 points per game with 234 passing yards per game and 72.3 rushing yards per game. Matthew Stafford has thrown for 761 yards, four touchdowns, and five interceptions for the Rams this season. Darrell Henderson Jr. has rushed for 111 yards and one touchdown, while Cooper Kupp has caught 28 passes for 280 yards and three scores for Los Angeles. The Los Angeles defense is allowing 23.3 points per game and 346.3 yards per game.

The San Francisco 49ers are 1-2 this season after they lost to Denver by a score of 11-10 last week. San Francisco led for most of this game, but gave up a touchdown with 4:10 left in the fourth quarter for the loss. The San Francisco offense is averaging 15.7 points per game with 172.7 passing yards per game and 151 rushing yards per game. Jimmy Garoppolo has thrown for 365 yards, two touchdowns, and one interception for the 49ers this season. Jeff Wilson Jr. (questionable) has rushed for 181 yards, while Brandon Aiyuk has caught 10 passes for 142 yards and one touchdown for San Francisco. The San Francisco defense is giving up 12.3 points per game and 227 yards per game.

Los Angeles is 4-1 ATS in their last 5 Monday games and 0-4 ATS in their last 4 Week 4 games. The under is 4-1 in Los Angeles’ last 5 games. San Francisco is 5-0 ATS in their last 5 home games and 14-4 ATS in their last 18 Monday games. The under is 10-1 in San Francisco’s last 11 games. The underdog is 7-0 ATS in these two teams last 7 head to head meetings.

Los Angeles comes into this game 2-1 this season, but almost gave up a big lead against Atlanta and was outgained by Arizona. San Francisco did not look good offensively against Denver or Chicago this season, but did score 27 points against Seattle. The 49ers should find some success against the LA defense, while you know the Rams will score at least 20 points. I like the over here.

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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