Los Angeles Rams at Arizona Cardinals - 9/25/22 NFL Picks and Prediction

Arizona Cardinals (1-1) vs Los Angeles Rams (1-1)

Game Info: Sunday, September 25, 2022 at 4:25 pm (State Farm Stadium)

Betting Odds: Arizona Cardinals +3.5 -- Over/Under: 48.5 Click Here for the Latest Odds

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The Los Angeles Rams will play the Arizona Cardinals in Week 3 of the NFL regular season on Sunday afternoon at State Farm Stadium in Glendale, Arizona.

The Los Angeles Rams are 1-1 this season after they defeated the Atlanta Falcons by a score of 31-27 in Week 2. Los Angeles had a 31-10 lead in the fourth quarter and was able to hold off the comeback attempt by the Falcons. The Los Angeles offense is averaging 20.5 points per game with 231.5 passing yards per game and 58.5 rushing yards per game. Matt Stafford has thrown for 512 yards, four touchdowns, and five interceptions for the Rams this season. Darrell Henderson Jr. has rushed for 94 yards and one score, while Cooper Kupp has caught 24 passes for 236 yards and three touchdowns for the Rams. The Los Angeles defense is giving up 29 points per game and 337 yards per game.

The Arizona Cardinals are 1-1 this season after they defeated the Las Vegas Raiders by a score of 29-23 in overtime in their last game. Arizona trailed 23-7 in the fourth quarter of this game, but was able to score 16 points in the fourth quarter to force overtime and scored on a fumble return touchdown in overtime for the win. The Arizona offense is averaging 25 points per game with 224.5 passing yards per game and 123 rushing yards per game. Kyler Murray has thrown for 470 yards, three touchdowns, and one interception, while also rushing for 57 yards and one touchdown for the Cardinals this season. Darrel Williams has rushed for 59 yards and one touchdown, while Greg Dortch has caught 11 passes for 118 yards and one score for Arizona. The Arizona defense is allowing 33.5 points per game and 406 yards per game.

Los Angeles is 0-4 ATS in their last 4 games and 2-8 ATS in their last 10 games following an ATS loss. The over is 6-1 in Los Angeles’ last 7 September games. Arizona is 2-6 ATS in their last 8 games and 0-6 ATS in their last 6 home games. The over is 4-1 in Arizona’s last 5 home games. The Rams are 9-1-1 ATS in these two teams last 11 head to head meetings.

Los Angeles avoided a near collapse in the fourth quarter of their last game, while Arizona was able to complete a huge comeback against the Raiders. Los Angeles has struggled on defense this season and will face a good offensive attack in this game. I don’t trust this Rams defense, so I am going to take Arizona with the points at home.

David’s Pick Arizona +3.5

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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