Los Angeles Chargers at Kansas City Chiefs - 9/15/22 NFL Picks and Prediction

Los Angeles Chargers at Kansas City Chiefs - 9/15/22 NFL Picks and Prediction Photo by Jayne Kamin-Oncea-USA TODAY Sports

Kansas City Chiefs (1-0) vs Los Angeles Chargers (1-0)

Game Info: Thursday, September 15, 2022 at 8:15 pm (GEHA Field at Arrowhead Stadium)

Betting Odds: Kansas City Chiefs -4.5 -- Over/Under: 53.5 Click Here for the Latest Odds

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The Los Angeles Chargers will play the Kansas City Chiefs in Week 2 of the NFL regular season at Arrowhead Stadium on Thursday Night Football.

The Los Angeles Chargers are 1-0 this season after they defeated the Las Vegas Raiders by a score of 24-19 in Week 1. The Chargers held Las Vegas to 320 yards of offense and forced three turnovers in the win. Justin Herbert threw for 279 yards and three touchdowns for the Chargers. Austin Ekeler rushed for 36 yards and caught four passes for 36 yards, while Keenan Allen caught four passes for 66 yards in the game. Keenan Allen has been ruled out for this game due to a hamstring injury.

The Kansas City Chiefs are 1-0 this season after they beat Arizona by a score of 44-21 in their last game. Kansas City dominated this game and led 23-7 at halftime. The Chiefs out gained Arizona by a total of 488-282. Patrick Mahomes threw for 360 yards and five touchdowns in the Chiefs win. Isiah Pacheco rushed for 62 yards and one score, while Travis Kelce caught eight passes for 121 yards and one touchdown in the game. The Kansas City defense gave up 282 yards and held Arizona to 3-12 on third down attempts.

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Los Angeles is 3-7 ATS in their last 10 games against the AFC West and 5-2 ATS in their last 7 Thursday games. The over is 4-0 in Los Angeles’ last 4 Thursday games, and the over is 5-1 in their last 6 games against the AFC. Kansas City is 6-1 ATS in their last 7 home games and 9-3 ATS in their last 12 games overall. The over is 8-1 in Kansas City’s last 9 games, and the over is 5-1 in Kansas City’s last 6 Thursday games. The road team is 16-5-1 ATS in these two team's last 22 head-to-head meetings.

This is going to be a very exciting game between two of the best AFC teams this season. It is a short week for both of these teams, so it is possible we see some sloppy play, especially early on. Kansas City looked fantastic on offense against Arizona, and I expect them to move the ball on the Chargers defense. The Chargers had chances to score more points against the Raiders in their last game, but weren’t able to pull away. I am taking the over in this game.

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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