San Francisco 49ers at Jacksonville Jaguars: 11/21/21 NFL Picks and Prediction

Jacksonville Jaguars (2-7) vs San Francisco 49ers (4-5)

Game Info: Sunday, November 21, 2021 at 1:00 pm (TIAA Bank Field)

Betting Odds: Jacksonville Jaguars +6.5 -- Over/Under: 47.5 Click Here for the Latest Odds

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The San Francisco 49ers will travel to TIAA Bank Field to take on the Jacksonville Jaguars this Sunday afternoon in NFL action.

The San Francisco 49ers improved to 4-5 on the season after defeating the Los Angeles Rams, 31-10, this past Monday night. San Francisco was outstanding defensively against the high-powered Los Angeles offense and had no trouble securing the victory after going into halftime with a 21-7 lead. San Francisco outgained Los Angeles by a 335-278 margin and won the turnover battle by a 2-0 margin in the victory. Leading the way for the 49ers was WR Deebo Samuel who had 5 receptions for 97 yards & 1 TD while also adding 36 rushing yards & 1 TD on 5 carries.

On the season, San Francisco is averaging 24.0 ppg on 372.3 total yards per game (254.4 passing yds/g; 117.9 rushing yds/g). Offensively, San Francisco has been led by WR Deebo Samuel who has 54 receptions for 979 yards & 5 TD while also adding 58 rushing yards & 2 TD. QB Jimmy Garoppolo has completed 66.4% of his passes for 1936 yards (246.3 passing yds/g), 10 TD, & 5 INT. The other top receivers for the 49ers outside of Deebo Samuel have been George Kittle (30 rec, 378 yards, 2 TD) & Brandon Aiyuk (22 rec, 256 yards, 2 TD). Leading the way for the 49ers backfield has been Elijah Mitchell who has 560 rushing yards & 3 TD on 116 carries.

Defensively, San Francisco is allowing their opponents to average 23.6 ppg on 348.2 total yards per game (225.4 passing yds/g; 122.8 rushing yds/g).

The Jacksonville Jaguars dropped to 2-7 on the season after being defeated by the Indianapolis Colts, 23-17, this past Sunday. Jacksonville fought back from an early 17-0 deficit to make it a game late after a 1-yard TD run by James Robinson put the Jaguars behind by just a 20-17 margin, however, Indianapolis came up big defensively late and was able to seal the victory after sacking and recovering a Trevor Lawrance fumble with under a minute left in the 4th quarter. Jacksonville outgained Indianapolis by a 331-295 margin, however, lost the turnover battle by a 1-0 margin in the loss. Leading the way for the Jaguars was James Robinson who had 12 carries for 57 yards & 1 TD.

On the season, Jacksonville is averaging 16.6 ppg on 343.0 total yards per game (224.0 passing yds/g; 119.0 rushing yds/g). Offensively, Jacksonville has been led by RB James Robinson who has 539 rushing yards & 6 TD on 100 carries. QB Trevor Lawrence has completed 58.0% of his passes for 1983 yards (239.1 passing yds/g), 8 TD, & 9 INT. The top receiving threats for the Jaguars have been Marvin Jones Jr. (38 rec, 434 yards, 3 TD), Laviska Shenault Jr. (35 rec, 358 yards), & Dan Arnold (27 rec, 315 yards).

Defensively, Jacksonville is allowing their opponents to average 25.8 ppg on 380.8 total yards per game (274.8 passing yds/g; 106.0 rushing yds/g).

The 49ers are 1-4 ATS in their last 5 games vs. a team with a losing record and 1-5 ATS in their last 6 games following a ATS win. The Jaguars are 5-1 ATS in their last 6 November games and 4-1 ATS in their last 5 games vs. a team with a losing record.

San Francisco is coming off an impressive victory against Los Angeles, however, this is still a team that recently loss to an Arizona Cardinals team that did not have Kyler Murray and have struggled at times defensively this season. Jacksonville hasn’t won many games, however, outside of their game at Seattle, has played well over the last month and have been led by the a defense that over the past two weeks has held two high-powered offenses in Buffalo & Indianapolis to just a combined 23 points. I’m expecting a letdown by San Francisco in this one and as I think Jacksonville can keep this one competitive at home, I’m taking the Jaguars and the points. Good Luck!

Brett’s Pick Jacksonville Jaguars +6.5

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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