Seattle Seahawks at San Francisco 49ers: 10/3/21 NFL Picks and Prediction

San Francisco 49ers (2-1) vs Seattle Seahawks (1-2)

Game Info: Sunday, October 3, 2021 at 4:05 pm (Levi's Stadium)

Betting Odds: San Francisco 49ers -3 -- Over/Under: 52 Click Here for the Latest Odds

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The Seattle Seahawks will travel to Levi’s Stadium to take on the San Francisco 49ers this Sunday afternoon in NFL action.

The Seattle Seahawks lost their 2nd straight game and dropped to 1-2 on the season after being defeated by the Minnesota Vikings, 30-17, this past Sunday. Seattle struggled slowing down the Minnesota offensive attack, despite the absence of Dalvin Cook, and could not fight back after going into halftime trailing by a 21-17 margin. Seattle was outgained by Minnesota by a 453-389 margin and didn’t force a turnover in the loss. Leading the way for the Seahawks was WR DK Metcalf who had 6 receptions for 107 yards & 1 TD.

On the season, Seattle is averaging 25.0 ppg on 406.0 total yards per game (298.3 passing yds/g; 107.7 rushing yds/g). Offensively, Seattle is led by QB Russell Wilson who has completed 73.3% of his passes for 895 yards, 7 TD, & 0 INT. The top receiving threats for the Seahawks have been Tyler Lockett (16 rec, 309 yards, 3 TD), DK Metcalf (16 rec, 220 yards, 2 TD), Freddie Swain (6 rec, 105 yards, TD), & Gerald Everett (8 rec, 77 yards, TD). Leading the way for the Seattle backfield has been Chris Carson who has 202 rushing yards & 3 TD’s on 41 carries.

Defensively, Seattle is allowing their opponents to average 26.3 ppg on 462.0 total yards per game (307.0 passing yds/g; 155.0 rushing yds/g).

The San Francisco 49ers dropped to 1-2 on the season after being defeated by the Green Bay Packers, 30-28, this past Sunday night. San Francisco fought back from a 17-0 deficit to take a late lead on a Kyle Juszczyk TD with just :37 seconds left in the 4th quarter, however, the 49ers had no answers for Aaron Rodgers late and the Packers were able to win the game on a 51-yard FG by Mason Crosby as time expired. San Francisco was outgained by Green Bay by a 353-298 margin and lost the turnover battle by a 2-0 margin in the loss. Leading the way for the 49ers was QB Jimmy Garoppolo who completed 25 of 40 passes for 257 yards, 2 TD, & 1 INT.

On the season, San Francisco is averaging 28.7 ppg on 360.0 total yards per game (255.0 passing yds/g; 105.0 rushing yds/g). Offensively, San Francisco is led by the WR duo of Deebo Samuel (20 rec, 334 yards, TD) & George Kittle (15 rec, 187 yards). QB Jimmy Garoppolo has completed 67.4% of his passes for 760 yards, 4 TD & 1 INT. Rookie QB Trey Lance hasn’t been used much, but has helped the 49ers to find the endzone twice this season and certainly will be used in specific packages. The 49ers backfield has already been banged up this season as they lost Raheem Mostert in Week 1 and was without both Elijah Mitchell & JaMycal Hasty last week. As of right now, Elijah Mitchell (36 att, 146 yards, TD) is currently questionable and Trey Sermon (11 att, 39 yards, TD) would be the lead back if Mitchell can’t go.

Defensively, San Francisco is allowing their opponents to average 24.7 ppg on 385.3 total yards per game (263.0 passing yds/g; 122.3 rushing yds/g).

The Seahawks are 4-1 ATS in their last five Week 4 games and 11-4 ATS in their last 15 games as an underdog. The 49ers are 8-3 ATS in their last 11 games in Week 4, however, are just 1-4 ATS in their last 5 home games.

Seattle hasn’t looked great over the last two weeks, but there is no question that this team has plenty of offensive talent to keep up with the 49ers, especially as the 49ers secondary will be without both Josh Norman & K’Waun Williams. San Francisco has some question marks in their backfield due to a bunch of injuries and as I just think Seattle responds with a big performance against their division rivals in this one, I think the play here is to take Seattle and the points. Good Luck!

Brett’s Pick Seattle Seahawks +3

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The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

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