Green Bay Packers at San Francisco 49ers 9/26/21 NFL Picks and Predictions

Green Bay Packers at San Francisco 49ers 9/26/21 NFL Picks and Predictions Photo by MARK HOFFMAN/MILWAUKEE JOURNAL SENTINEL via Imagn Content Services, LLC

San Francisco 49ers (2-0) vs Green Bay Packers (1-1)

Game Info: Sunday, September 26, 2021 at 8:20 pm (Levi's Stadium)

Betting Odds: San Francisco 49ers -3 -- Over/Under: 48 Click Here for the Latest Odds

Where to Watch: NBC Stream live sports and exclusive originals on ESPN+. Sign up now! Advertisement

The Green Bay Packers face the San Francisco 49ers on Sunday, September 26th, at Levi's Stadium for a Week 3 NFL matchup. 

The Green Bay Packers bounced back in a big way after their Week 1 debacle in Jacksonville. The Packers defeated their NFC North rivals in the Detroit Lions at Lambeau by the final score of 35-17 to get to 1-1. The Packers' defense was not the strongest in the first half of that game, in fact, the Packers trailed Detroit by three at the break. Green Bay made some adjustments at halftime and dominated the second half, coming back and covering the 11.5-point spread rather easily. The Packers' defense was able to put pressure on Jared Goff which was something we did not see in the first half. Aaron Rodgers and Aaron Jones both had excellent nights for Green Bay as Rodgers had three passing touchdowns and Jones had four total touchdowns. The Packers will now face a tough opponent in the 49ers on the road. 

The San Francisco 49ers moved to 2-0 on the year after taking down the Philadelphia Eagles in a 17-11 defensive battle. The 49ers have had to deal with various injuries this season, especially at the running back position. Raheem Mostert was ruled out for the season after Week 1, and now Trey Sermon, Elijah Mitchell, and JaMycal Hasty are all banged up after the Week 2 contest at Philly. This will be the first home game of the season for the 49ers as they took on both the Lions and Eagles on the road. The 49ers have been able to get it done on both sides of the ball, but this will certainly be the toughest matchup the Niners have seen yet this season. Jimmy Garoppolo is 39 of 55 for 503 passing yards and two passing touchdowns as he has taken almost all of the snaps at QB this season, with Trey Lance making a few appearances here and there. 

Get the BEST EXPERT PICKS From Top Handicappers

The San Francisco 49ers are a 3-point favorite and the total is set at 50. This should be yet another entertaining primetime game during Sunday Night Football. I think that both teams are going to be able to move the football and we are going to see yet another high-scoring primetime contest. I will take the over, but I am not rushing to the window for this one. 

$1001 Match Bet + FREE NBA JERSEY WITH $100 BET!!!!!

The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

Free NFL Parlay For Today 12/5/21 NFL Pick & Prediction NFL Betting

Guaranteed Packages

Guaranteed packages automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.

Dismiss