Buffalo Bills at San Francisco 49ers: 12/7/20 NFL Picks and Prediction

Buffalo Bills at San Francisco 49ers: 12/7/20 NFL Picks and Prediction Photo by Kirby Lee-USA TODAY Sports

San Francisco 49ers (5-6) vs Buffalo Bills (8-3)

Game Info: Monday, December 7, 2020 at 8:15 pm (Levi's Stadium)

Betting Odds: San Francisco 49ers +2.5 -- Over/Under: 48 Click Here for the Latest Odds

Where to Watch: ESPN Stream live sports and exclusive originals on ESPN+. Sign up now! Advertisement

The Buffalo Bills and San Francisco 49ers will square off at State Farm Stadium this upcoming Monday night in NFL action.

The Buffalo Bills improved to 8-3 on the season after defeating the Los Angeles Charges, 27-17, this past Sunday. Buffalo was committed three turnovers, however, the defense was solid on keeping Los Angeles off the scoreboard and the Bills were able to pull away after taking a 24-6 lead early in the 3rd quarter on a 3-yard TD run by Josh Allen. Buffalo was outgained by Los Angeles by a 367-332 margin, however, won the turnover battle by a 3-1 margin in the victory. Leading the way for the Bills was QB Josh Allen who completed 18 of 24 passes for 157 yards, 1 TD, & 1 INT while also adding a rushing TD.

On the season, Buffalo is averaging 27.2 ppg on 384.5 total yards per game (280.2 passing yds/g; 104.4 rushing yds/g). Offensively, Buffalo has been led by QB Josh Allen who has completed 68.8% of his passes for 3,028 yards (304.6 yds/g), 22 TD, & 8 INT. Allen is also the 2nd leading rusher for the Bills as he has 311 yards & 6 TD’s on 81 carries. The top receiving threats for the Bills have been Stefon Diggs (80 rec, 945 yards, 4 TD), Cole Beasley (57 rec, 667 yards, 3 TD), John Brown (29 rec, 386 yards, 2 TD), and Gabriel Davis (22 rec, 354 yards, 4 TD). Leading the way for the Buffalo backfield is the duo of Devin Singletary (110 att, 483 yards, TD) and Zack Moss (68 att, 283 yards, 3 TD).

Get 15% OFF ALL Premium Pick and Package Purchases in August use code: aug15 (no limit) !!!!!

Defensively, Buffalo is allowing their opponents to average 25.6 ppg on 387.8 total yards per game (258.2 passing yds/g; 129.6 rushing yds/g).

The San Francisco 49ers snapped their 3-game losing streak and improved to 5-6 on the season after upsetting the Los Angeles Rams, 23-20, this past Sunday. The San Francisco defense did an outstanding job of slowing down the Los Angeles offensive attack and was able to secure the victory on a game-winning 42-yard FG by Robbie Gould as time expired. San Francisco outgained Los Angeles by a 348-308 margin and forced Los Angeles into committing 4 turnovers in the victory. Leading the way for the 49ers was WR Deebo Samuel who has 11 receptions for 133 yards.

On the season, San Francisco is averaging 23.7 ppg on 382.3 total yards per game (270.0 passing yds/g; 112.3 rushing yds/g). Offensively, San Francisco is led by RB Raheem Mostert who has 346 yards & 2 TD’s on 67 attempts. Mostert returned from injury last week and is also joined in the backfield with Jerick McKinnon (80 att, 315 yards, 5 TD), Jeff Wilson Jr. (50 att, 206 yards, 4 TD), and Tevin Coleman (21 att, 50 yards). QB Nick Mullens (67.5 Comp %, 1,642 yards, 6 TD, 7 INT) will continue to start for the injured Jimmy Garoppolo (67.1 Comp %, 1,096 yards, 7 TD, & 5 INT). The top receiving threats for the 49ers have been George Kittle (37 rec, 474 yards, 2 TD), Brandon Aiyuk (35 rec, 446 yards, 3 TD), Kendrick Bourne (32 rec, 412 yards, 1 TD), and Deebo Samuel (27 rec, 318 yards, TD). The 49ers will be without George Kittle however, they do have a chance of having Brandon Aiyuk back in the lineup.

Defensively, San Francisco is holding their opponents to an average of 23.1 ppg on 326.4 total yards per game (217.6 passing yds/g; 108.7 rushing yds/g).

The Bills are 9-4-2 ATS in their last 15 road games, however, are just 1-4 ATS vs. a team with a losing record. The 49ers are 13-3 ATS in their last 16 Monday games and 7-3 ATS in their last 10 home games vs. a team with a winning road record.

Buffalo comes into with an 8-3 record, however, I haven’t been a huge fan with how the Bills have looked as of late as they weren’t impressive in recent victories against the Jets & Patriots and were a bit off in their win against the Chargers. San Francisco picked up a huge win against the Rams and between the fact that their offense got back two of their main weapons in Raheem Mostert & Deebo Samuel and that I think their defense will have another strong performance, I think the play here to take San Francisco and the points. Good Luck!

Risk Free Bets, Free Bets and Deposit Bonuses CLICK HERE!!!!

Brett’s Pick San Francisco 49ers +2.5

Get Premium Picks Start Winning Now »
The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

Mitch's Take...

San Francisco 49ers vs Buffalo Bills 12/7/20 NFL Pick and Prediction Monday Week 13 NFL

Credit Guaranteed Packages

Packages with Credit Guarantees automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a credit guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.

Dismiss