Free Picks Philadelphia Eagles at San Francisco 49ers: NFL Picks and Prediction 10/4/20

Defensively, Philadelphia is allowing their opponents to average 29.0 ppg on 358.7 total yards per game (252.3 passing yds/g; 106.3 rushing yds/g).

The San Francisco 49ers won their 2nd straight game and improved to 2-1 on the season after defeating the New York Giants, 36-9, this past Saturday. San Francisco had a ton of injuries coming into this game as they were missing Jimmy Garoppolo, Raheem Mostert, and George Kittle on the offensive end, however, the 49ers still dominated the Giants on both sides of the ball and had no trouble pulling away after taking a 23-9 lead late in the 3rd quarter. San Francisco outgained New York by a 420-231 margin and won the turnover battle by a 3-0 margin in the victory. Leading the way for the 49ers was QB Nick Mullens who completed 25 of 36 passes for 343 yards and a TD.

On the season, San Francisco is averaging 29.0 ppg on 400.7 total yards per game (268.0 passing yds/g; 132.7 rushing yds/g). Offensively, San Francisco has been led by RB Raheem Mostert who has 148 yards and a TD on 23 carries while also hauling in 7 receptions for 110 yards and a TD in the passing attack. Mostert is questionable for this week, however, the 49ers have capable backups in Jerick McKinnon (20 att, 139 yards, 2 TD) & Jeff Wilson Jr. (14 att, 18 yds, TD). Jimmy Garoppolo (67.3 comp %, 390 yards, 4 TD) has a chance to be back, however, the 49ers did not seem to miss a beat with Mullens behind center. George Kittle (4 rec, 44 yards) looks close to being back. In his absence, the top receivers for the 49ers have been Kendrick Bourne (10 rec, 164 yards), Brandon Aiyuk (7 rec, 91 yards), and Jordan Reed (11 rec, 85 yards, 2 TD).

Defensively, San Francisco is holding their opponents to an average of 15.3 ppg on 312.7 total yards per game (196.0 passing yds/g; 116.7 rushing yds/g).

The Eagles are 5-2 ATS in their last 7 games as a road underdog, however, are 0-4 ATS in their last 4 games overall. The 49ers are 5-1 ATS in their last 6 games as a favorite and 5-2 ATS in their last 7 games overall.

San Francisco has been able to pick up a couple of wins despite having more injuries to key players than I can remember, however, I think a lot of it has been due to their competition as they’ve had the luxury of playing two of the worst teams in the NFL in the Jets & Giants. The 49ers schedule continues to look easy as Philadelphia has been one of the biggest disappointments early this season as both the Eagles offense and defense has struggled. San Francisco lost Nick Bosa & Solomon Thomas on the defensive end, however, this is still a strong defense that should have success against a struggling Carson Wentz that could be without two of his top targets (Goedert & Jackson). Overall, as I think either Jimmy Garoppolo or Nick Mullens will be able to have success at home against the Philadelphia defense, I am going to take San Francisco to cover this home spread. Good Luck!